II. Pathophysiology

  1. Waves of peristalsis occur simultaneously
  2. Peristalsis preserved to some extent

III. Diagnosis

  1. Esophageal manometry

IV. Management: Treat underlying cause for spasm

  1. Medications may be ineffective
  2. Reflux Esophagitis
    1. Antisecretory therapy (e.g. Proton Pump Inhibitor)
  3. Mood Disorder
    1. Reassurance
    2. Selective Serotonin Reuptake Inhibitors (SSRI)
    3. Anxiolytics
    4. Tricyclic Antidepressants
  4. Achalasia
    1. See Esophageal Achalasia
  5. Antispasmodics
    1. Nitroglycerin
    2. Calcium Channel Blockers
      1. Nifedipine 10 mg capsule
        1. Bite and swallow capsule 30 minutes before meal

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Related Studies

Ontology: Esophageal spasm (C0014863)

Definition (MSH) A hypermotility disorder of the ESOPHAGUS that is characterized by spastic non-peristaltic responses to SWALLOWING; CHEST PAIN; and DYSPHAGIA.
Concepts Disease or Syndrome (T047)
MSH D015155
ICD10 K22.4
SnomedCT 79962008, 196614005, 68681007
English Diffuse Esophageal Spasm, Diffuse Esophageal Spasms, Esophageal Spasm, Esophageal Spasm, Diffuse, Esophageal Spasms, Esophageal Spasms, Diffuse, Spasm, Diffuse Esophageal, Spasm, Esophageal, Spasms, Diffuse Esophageal, Spasms, Esophageal, ESOPHAGOSPASM, OESOPHAGOSPASM, DOS - Diffuse oeso spasm, ESOPHAGEAL SPASM DIFFUSE, OS - Esophageal spasm, diffuse esophageal spasm (diagnosis), diffuse esophageal spasm, ES - Oesophageal spasm, Spasm esophageal, Esophageal Spasm, Diffuse [Disease/Finding], dysmotility esophageal, esophageal spasm, corkscrew esophagus, diffuse esophageal spasms, esophageal motor disorder, spasm esophageal, dyskinesia esophagus, esophagospasms, esophagus spasm, oesophageal motility disorder, oesophageal spasms, esophageal motility disorder, Spasm;oesophageal, oesophagus spasm, diffuse oesophageal spasm, oesophagus spasms, disorders esophageal motor, dyskinesia of esophagus, esophageal dysmotility, esophageal spasms, spasm of oesophagus, esophagospasm, esophagus spasms, oesophageal dysmotility, spasm of esophagus, Spasm oesophageal, Esophagospasm (disorder), Esophagospasm, Diffuse spasm of esophagus, Esophagism, Spasm of esophagus, DOS - Diffuse esophageal spasm, DOS - Diffuse oesophageal spasm, Diffuse esophageal spasm, Diffuse oesophageal spasm, Oesophageal spasm, Oesophagospasm, Diffuse spasm of oesophagus, Oesophagism, Spasm of oesophagus, OS - Oesophageal spasm, Diffuse spasm of esophagus (disorder), ES - Esophageal spasm, Esophageal spasm, esophagismus, esophagus; spasm, spasm; esophagus, Spasm;esophageal, oesophageal spasm
French SPASME OESOPHAGIEN, Spasme oesophagien, Spasme de l'oesophage
Portuguese ESPASMO ESOFAGICO, Esofagospasmo, Espasmo esofágico, Espasmo Esofágico Difuso, Espasmo Esofágico
Dutch slokdarmspasme, oesofagusspasmen, oesofageale spasmen, slokdarmspasmen, spasmen oesofageaal, oesofagus; spasme, spasme; oesofagus, oesofagusspasme, Oesofagusspasme, Slokdarmspasme, Spasme, oesofagus-, Spasme, slokdarm-
German Spasmus des Oesophagus, OESOPHAGUSSPASMUS, Oesophagusspasmus, Krampf, ösophagealer, Krampf, Speiseröhren-, Ösophagospasmus, diffuser, Ösophagospasmus, Ösophagusspasmus, diffuser, Ösophagusspasmus, Spasmen, ösophageale, Speiseröhrenkrampf
Italian Esofagospasmo, Spasmo esofageo, Spasmo esofageo diffuso
Spanish Esofagoespasmo, Espsmo esofágico, ESOFAGOSPASMO, espasmo de esófago, espasmo esofágico, esofagoespasmo, espasmo de esófago (concepto no activo), esofagismo, espasmo difuso del esófago (trastorno), espasmo difuso del esófago, Espasmo esofágico, Espasmo Esofágico Difuso, Espasmo Esofágico
Swedish Esofaguskramp
Japanese ショクドウケイレン, けいれん-食道, 食道けいれん, びまん性食道痙攣, 汎発性食道痙攣, 瀰漫性食道痙攣, 食道痙攣-瀰漫性, 食道痙攣, びまん性食道けいれん, 汎発性食道けいれん, 痙攣-食道, 食道けいれん-びまん性, 食道痙攣-びまん性, 食道痙攣-び漫性, 食道痙攣-汎発性
Finnish Diffuusi ruokatorven spasmi
Czech Jícnový spasmus, Spasmus jícnu, ezofágus - spazmus difuzní, difúzní jícnový spazmus
Polish Skurcz przełyku rozlany
Hungarian Nyelőcső görcs, Oesophagospasmus, Oesophagealis görcs, Oesophagus görcse, Nyelőcsőgörcs
Norwegian Spiserørskramper, diffuse, Øsofaguskramper, Øsofaguskramper, diffuse, Spiserørskramper, Diffuse øsofaguskramper, Diffuse spiserørskramper