II. Pathophysiology

  1. Severe Retching results in tear in esophageal mucosa
  2. Lesion occurs near esophagogastric junction

III. Epidemiology

  1. Incidence: 7.3 per 100,000

IV. Symptoms

  1. Hematemesis follows episode of Retching or Vomiting

V. Signs

VI. Differential Diagnosis

VII. Diagnosis

  1. Endoscopy (EGD)
    1. Mucosal tear directly visualized

VIII. Course

  1. Most spontaneously heal
  2. However, bleeding related mortality approaches that of Peptic Ulcer Bleeding (esp. age >65 and comorbidity)

IX. Management

  1. Generally heals spontaneously within several days
  2. Endoscopy for cauterization if needed
  3. Surgery rarely required

X. References

  1. Ljubicic (2014) Scand J Gastroenterol 49(4): 458-64 +PMID:24495010

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Ontology: Mallory-Weiss Syndrome (C0024633)

Definition (MSHCZE) Stav charakterizovaný krvácením z lineárních ruptur v oblasti ezofagogastrické junkce. Vzniká při silném zvracení, někdy u alkoholiků; jedna z příčin HEMATEMEZE. (cit. Velký lékařský slovník online, 2012 http://lekarske.slovniky.cz/ )
Definition (NCI) A disorder characterized by upper gastrointestinal tract bleeding caused by longitudinal mucosal tears in the gastroesophageal junction. The tears result from retching or forceful coughing. It was initially described in alcoholics.
Definition (MSH) A condition characterized by mucosal tears at the ESOPHAGOGASTRIC JUNCTION, sometimes with HEMATEMESIS. Typically it is caused by forceful bouts of retching or VOMITING.
Concepts Disease or Syndrome (T047)
MSH D008309
ICD9 530.7
ICD10 K22.6
SnomedCT 35265002, 155678004, 196620006, 307131005
English Mallory Weiss Syndrome, Mallory-Weiss Syndrome, Syndrome, Mallory-Weiss, MALLORY-WEISS SYNDROME, Gastro-oeso lac-haem syn, MALLORY WEISS SYNDROME, Gastresophageal laceration-hemorrhage syndrome, Gastroesophageal laceration-hemorrhage syndrome, Gastrooesophageal laceration-hemorrhage syndrome, gastroesophageal laceration-hemorrhage syndrome, Mallory Weiss syndrome (diagnosis), Mallory Weiss syndrome, Mallory Weiss tear, Mallory-weiss syndrome, Gastroesophageal laceration syndrome, Mallory-Weiss Syndrome [Disease/Finding], Gastroesophageal Laceration-Hemorrhage, Mallory Weiss Laceration, Mucosal Lacerations Gastroesophageal Junction, Lacerations-Gastroesophageal Junction, Mucosal, Mallory-Weiss Tear, Mallory Weiss Tear, Junction, Mucosal Lacerations-Gastroesophageal, Laceration, Mallory-Weiss, Lacerations-Gastroesophageal Junctions, Mucosal, Mucosal Lacerations-Gastroesophageal Junctions, Gastroesophageal Laceration Hemorrhage, Mucosal Lacerations-Gastroesophageal Junction, Laceration-Hemorrhages, Gastroesophageal, Mallory-Weiss Laceration, Junctions, Mucosal Lacerations-Gastroesophageal, Laceration-Hemorrhage, Gastroesophageal, Gastroesophageal Laceration-Hemorrhages, esophagus tears, mallory weiss syndrome, esophagus tearing, mallory weiss tearing, mallory weiss tears, mallory-weiss tear, mallory-weiss syndrome, mallory tears weiss, esophagus tear, Gastrooesophageal laceration-haemorrhage syndrome, mallory weiss tear, Mallory-Weiss tear (diagnosis), Mallory-Weiss syndrome, Gastro-esophageal laceration-hemorrhage syndrome, Gastro-oesophageal laceration-haemorrhage syndrome, Mallory-Weiss tear, Mallory-Weiss syndrome (disorder), Mallory-Weiss tear (disorder), Mallory-Weiss, gastroesophageal; laceration-hemorrhage syndrome, syndrome; gastroesophageal laceration-hemorrhage
Portuguese SINDROME DE MALLORY-WEISS, Síndrome de laceração-hemorragia gastresofágica, Rasgadura de Mallory-Weiss, Síndrome de Mallory-Weiss
Dutch Mallory-Weiss-scheur, gastro-oesofageal laceratie-hemorragie-syndroom, gastro-oesofageale bloedende laceraties syndroom, gastro-oesofagaal; laceratiebloeding-syndroom, syndroom; gastro-oesofagale laceratiebloeding, Gastro-oesofagaal laceratie-bloedingssyndroom, syndroom van Mallory-Weiss, Mallory-Weiss-syndroom, Syndroom van Mallory-Weiss, Syndroom, Mallory-Weiss-
French Syndrome de dilacération hémorragique gastro-oesophagienne, Syndrome de déchirure-hémorragie de l'oesophage, Syndrome gastro-oesophagien de déchirure-hémorragie, Déchirure de Mallory-Weiss, SYNDROME DE MALLORY-WEISS, Syndrome de Mallory-Weiss
German Mallory-Weiss-Syndrom (blutende Schleimhauteinrisse von Magen und Speiseroehre), Mallory-Weiss-Schleimhauteinriss, Mallory-Weiss Syndrom, Mallory-Weiss-Syndrom
Italian Sindrome con lacerazione ed emorragia gastroesofagea, Sindrome da lacerazione-emorragia gastroesofagea, Lacerazione di Mallory Weiss, Sindrome di Mallory-Weiss
Spanish Desgarro de Mallory-Weiss, Síndrome de desgarro y hemorragia gastroesofágicos, Síndrome de laceración gastroesofágica y hemorragia, desgarro de Mallory-Weiss (trastorno), desgarro de Mallory-Weiss, síndrome de Mallory - Weiss (trastorno), síndrome de Mallory - Weiss, síndrome de Mallory-Weiss, síndrome de laceración hemorrágica gastroesofágica, Síndrome de Mallory-Weiss
Japanese マロリー・ワイス裂傷, マロリー・ワイス症候群, マロリーワイスショウコウグン, マロリーワイスレッショウ, ショクドウイセツゴウブレッショウシュッケツショウコウグン, 食道胃接合部裂傷出血症候群
Swedish Mallory-Weiss syndrom
Czech Malloryho-Weissův syndrom, Syndrom Mallory-Weissův, Mallory-Weissův syndrom, ezofagogastrická trhlina
Finnish Mallory-Weissin oireyhtymä
Russian MELLORI-VEISA SINDROM, МЭЛЛОРИ-ВЕЙСА СИНДРОМ
Korean 위-식도 열상-출혈 증후군
Polish Uszkodzenie połączenia przełyku z żołądkiem, Zespół Boerhaave'a, Zespół Mallory'ego-Weissa
Hungarian Gastrooesophagealis laceratio-vérzés syndroma, Gastro-oesophagealis laceratio-vérzés tünetegyüttes, Gastrooesophagealis laceratio-vérzés szindróma, Mallory Weiss hasadék, Mallory-Weiss syndroma
Norwegian Mallory-Weiss’ syndrom

Ontology: Laceration of esophagus (C0347629)

Definition (NCI) A torn, ragged, mangled wound, or an accidental cut of esophagus.
Concepts Injury or Poisoning (T037)
SnomedCT 262793000
English Laceration Of Esophagus, Oesophageal laceration, laceration of esophagus (diagnosis), laceration of esophagus, Esophageal laceration, LACERATION(S) OF ESOPHAGUS, ESOPHAGUS, LACERATION(S) OF, Laceration of esophagus, Laceration of oesophagus, Laceration of esophagus (disorder)
Spanish Laceración esofágica, laceración esofágica (trastorno), laceración del esófago, laceración de esófago (trastorno), laceración de esófago, laceración esofágica
Dutch slokdarmlaceratie
German Oesophaguslazeration
Czech Lacerace jícnu, Ezofageální lacerace
Japanese 食道裂傷, ショクドウレッショウ
Portuguese Laceração esofágica
Italian Lacerazione esofagea
French Lacération oesophagienne
Hungarian Ooesophagealis laceratio, Oesophagealis laceratio