II. Indication
- Open Angle Glaucoma first line agent
III. Contraindications: Relative (related to systemic absorption risk described below)
- Asthma
- Chronic Obstructive Pulmonary Disease
- Congestive Heart Failure
- Cardiac conduction disturbance
- Depression
- Concurrent systemic Beta Blocker use
IV. Mechanism
- Decreases formation of Aqueous Humor
- Does not interfere with vision
V. Preparations
- Betaxolol (Betoptic): $39
- Only selective Beta Blocker eye drop (may be used in COPD, Asthma)
- Concentrations: 0.25%, 0.5%
- Dose: 1 gtt bid
- Levobunolol (Betagan): $29-34
- Concentrations: 0.25%, 0.5%
- Dose: 1 gtt qd-bid
- Metipranolol (OptiPranolol): $24
- Concentrations: 0.3%
- Dose: 1 gtt bid
-
Timolol (Timoptic): $30-35
- Concentrations: 0.25%, 0.5%
- Dose: 1 gtt bid
- Timoptic XE: $17-21
- Concentration: 0.25%, 0.5%
- Dose: 1 gtt qd
VI. Technique: Instillation
- See Don't Open Eyes Technique for Eye Drop Instillation
- Reduces systemic absorbtion
VII. Adverse effects
VIII. Reference
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Related Studies (from Trip Database) Open in New Window
| Levobunolol (on 6/18/2017 at Walmart.com) | ||
| Levobunolol 0.5% op soln (5ml) | #1 bottle for $4.00 | $4.00 each |
| Levobunolol 0.5% op soln (5ml) | #3 bottles for $10.00 | $3.33 each |
| betaxolol (on 5/17/2017 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| BETAXOLOL 10 MG TABLET | Generic | $0.67 each |
| BETAXOLOL HCL 0.5% EYE DROP | Generic | $8.84 per ml |
| betoptic (on 2/22/2017 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| BETOPTIC S 0.25% EYE DROPS | $27.57 per ml | |
| levobunolol (on 5/17/2017 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| LEVOBUNOLOL 0.5% EYE DROPS | Generic | $1.94 per ml |
| timoptic (on 1/6/2017 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| TIMOPTIC 0.5% OCUDOSE DROP | $6.65 each | |
| TIMOPTIC-XE 0.5% EYE SOLN | Generic | $16.83 per ml |
