II. Background

  1. Sulfuryl Fluoride is a gas used to fumigate coastal structures for termites
  2. Gas is colorless and odorless and accumulates in low areas (heavier than air)
  3. Humans are exposed via inhalation of gas
    1. Exposure limit over short term is 10 ppm
    2. Toxic or lethal dose 200 ppm

III. Adverse Effects

IV. Labs

  1. Serum Electrolytes and acid-base
    1. Serum Calcium Decreased
    2. Serum Magnesium decreased
    3. Serum Potassium decreased
    4. Acidosis

VI. Management

  1. Remove patient from exposure
  2. Decontamination
  3. ABC Management
  4. Electrolyte replacement
    1. Hypocalcemia Management
    2. Hypomagnesemia Management
    3. Hypokalemia Management
  5. Arrhythmia Management
    1. Consider Amiodarone for Ventricular Arrhythmia
  6. Seizure Management
    1. See Status Epilepticus
    2. Consider phenobarbital for refractory Seizures (after initial Benzodiazepines)
  7. Disposition - Emergency discharge indications (all others should remain for hospital observation)
    1. Observed for 4-6 hours without symptoms
    2. No acute EKG abnormalities (QTC normal, QRS width normal)
    3. No Hemodynamic instability

VII. References

  1. Tomaszewski (2020) Crit Dec Emerg Med 34(11): 28

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Related Studies

Ontology: sulfuryl fluoride (C0075613)

Concepts Hazardous or Poisonous Substance (T131) , Inorganic Chemical (T197)
MSH C048899
SnomedCT 4435007
English sulfonyl fluoride, sulfuryl fluoride, Sulfuryl fluoride, Sulfuryl fluoride (substance), Sulphuryl fluoride
Spanish sulfurilfluoruro (sustancia), sulfurilfluoruro