Definition (NCI)
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A highly toxic protein phytotoxin lectin and hemagglutin from the seeds of Ricinus communis, the castor oil plant. It agglutinates cells, is proteolytic, and causes lethal inflammation and hemorrhage if taken internally. It has N-glycosidase activity that cleaves 28S rRNA, halting protein synthesis; extreme cytotoxicity makes ricin an attractive candidate for artificial fusion with binding proteins to create cell-type-specific toxins.
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Definition (MSH)
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A protein phytotoxin from the seeds of Ricinus communis, the castor oil plant. It agglutinates cells, is proteolytic, and causes lethal inflammation and hemorrhage if taken internally.
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Definition (CSP)
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proteinaceous phytotoxin from the castor oil plant, Ricinus communis; A chain has glycosidase activity which cleaves 28S rRNA, halting protein synthesis; extreme cytotoxicity makes ricin an attractive candidate for artificial fusion with binding proteins to create cell-type-specific toxins.
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Concepts |
Hazardous or Poisonous Substance
(T131)
, Amino Acid, Peptide, or Protein
(T116)
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MSH |
D012276
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SnomedCT |
30096004
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LNC |
LP33246-7, LP35837-1, MTHU016499, MTHU018738 |
English |
Castor Bean Lectin, Lectin, Castor Bean, Lectin, Ricinus, Ricinus Lectin, Ricinus Toxin, Toxin, Ricinus, Ricins, RCA 60, RCA60, Ricin [Chemical/Ingredient], ricin, Ricin, Ricin toxin, RICIN, Ricin (substance), Ricinus Communis Agglutinin II |
Swedish |
Ricin
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Czech |
ricin
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Finnish |
Risiini
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Italian |
Ricino tossina, RCA 60, Lectina del seme di ricino, RCA60, Ricina, Lectina del ricinus, Lectina della ricina |
Russian |
LEKTIN, RICINUS, RITSIN, KLESHCHEVINY OBYKNOVENNOI LEKTIN, LEKTIN KLESHCHEVINY, LEKTIN KLESHCHEVINY OBYKNOVENNOI, КЛЕЩЕВИНЫ ОБЫКНОВЕННОЙ ЛЕКТИН, ЛЕКТИН, RICINUS, ЛЕКТИН КЛЕЩЕВИНЫ, ЛЕКТИН КЛЕЩЕВИНЫ ОБЫКНОВЕННОЙ, РИЦИН |
Japanese |
トウゴマレクチン, ひましレクチン, リシン(Ricin), ヒマシレクチン, レクチン-トウゴマ, レクチン-ヒマシ |
Polish |
Rycyna
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Spanish |
Lectina de Ricinus communis, ricino (sustancia), ricino, Lectina de Ricino, Lectina de Semilla de Higuera Infernal, Lectina de Semilla de Ricino, Ricina |
Portuguese |
Lectina de Ricinus communis, Lectina da Semente da Mamona, Lectina da Semente do Rícino, Lectina do Rícino, Ricina |
French |
Ricine
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German |
Kastorlektin, Lektin, Kastor-, Lektin, Rizinus-, Ricin |