Rhinitis Medicamentosa

Aka: Rhinitis Medicamentosa

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II. Pathophysiology

  1. Associated with topical agent use >5-7 days
  2. Tachyphylaxis associated with medications
    1. Nasal Decongestants (Afrin, Neo-Synephrine)
    2. Nasal spray preservative Benzalkonium chloride
  3. Other associated medications
    1. Reserpine
    2. Oral Contraceptive pills
    3. Inderal
    4. Aldomet

III. Symptoms

  1. Rebound nasal Congestion after nasal Decongestant

IV. Signs

  1. Fiery red edema at nasal mucosa

V. Management

  1. Intranasal Steroid (e.g. Vancenase)
  2. Withdrawal of nasal Decongestant

VI. Prevention

  1. Avoid prolonged use of nasal Decongestants

VII. Reference

  1. Graf (1997) J Allergy 52(40 suppl): 28-34 [PubMed]

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Ontology: Rhinitis medicamentosa (C0149980)

Concepts Disease or Syndrome (T047)
SnomedCT 95239003
Dutch medicamenteuze rhinitis, rhinitis medicamentosa
French Rhinite médicamenteuse
German Rhinitis medicamentosa, Rhinitis, von Medikamenten verursacht
Italian Rinite da farmaci
Portuguese Rinite medicamentosa
Spanish Rinitis medicamentosa, rinitis medicamentosa (trastorno), rinitis medicamentosa
Japanese 薬物性鼻炎, ﾔｸﾌﾞﾂｾｲﾋﾞｴﾝ
English rhinitis medicamentosa, rhinitis medicamentosa (diagnosis), Rhinitis medicamentous, Rhinitis medicamentosa, Rhinitis medicamentosa (disorder)
Czech Rýma medikamentózní, Medikamentózní rýma
Hungarian Gyógyszer okozta rhinitis
Derived from the NIH UMLS (Unified Medical Language System)

Related Topics in Pharmacology

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