II. Indications
- Peanut Allergy Desensitization in ages 4 to 17 years old
- Goal to reduce severity of reactions (NOT to reintroduce peanuts into diet)
- Alternative to peanut oral Immunotherapy (performed by allergists)
III. Efficacy
- Following 1 year of Desensitization, two thirds of children are expected to tolerate 2 peanuts without reaction
IV. Precautions
- Peanut free diet must be followed regardless of Desensitization
- Keep Epinephrine Autoinjector nearby (reactions will be more common during Desensitization)
V. Disadvantages
- Cost: $890 per month
- Must be in office to start medication and at each titration up in dose
- Restart in clinic if >3 doses missed
VI. Dosing
- Risk Evaluation and Mitigation Strategy (REMS) required for prescribers
- Taken daily and gradually increasing doses
VII. References
- (2020) Presc Lett 27(10): 58
