II. Indications

  1. Peanut Allergy Desensitization in ages 4 to 17 years old
    1. Goal to reduce severity of reactions (NOT to reintroduce peanuts into diet)
    2. Alternative to peanut oral Immunotherapy (performed by allergists)

III. Efficacy

  1. Following 1 year of Desensitization, two thirds of children are expected to tolerate 2 peanuts without reaction

IV. Precautions

  1. Peanut free diet must be followed regardless of Desensitization
  2. Keep Epinephrine Autoinjector nearby (reactions will be more common during Desensitization)

V. Disadvantages

  1. Cost: $890 per month
  2. Must be in office to start medication and at each titration up in dose
  3. Restart in clinic if >3 doses missed

VI. Dosing

  1. Risk Evaluation and Mitigation Strategy (REMS) required for prescribers
  2. Taken daily and gradually increasing doses

VII. References

  1. (2020) Presc Lett 27(10): 58

Images: Related links to external sites (from Bing)

Related Studies