II. Pathophysiology

  1. Categorized as a skin cancer

III. Risk Factors

  1. Prolonged Sun Exposure
  2. Tobacco Smoking (esp. Pipe smoking)

IV. Symptoms

  1. Recurrent or non-healing Lip Ulcer

V. Signs

  1. Ulcer with overlying crust
  2. Borders of ulcer are heaped up

VI. Course

  1. Contiguous spread of untreated tumors

VII. References

  1. Diaz in Noble (2001) Primary Care Medicine, p. 1757
  2. Weinberg (2002) Am Fam Physician 65(7):1379-86 [PubMed]

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Related Studies

Ontology: Lip Neoplasms (C0023761)

Definition (NCI) A benign or malignant neoplasm involving the lip.
Definition (MSH) Tumors or cancer of the LIP.
Concepts Neoplastic Process (T191)
MSH D008048
SnomedCT 126770008
English Lip Neoplasms, Neoplasm, Lip, Neoplasms, Lip, LIP NEOPL, NEOPL LIP, neoplasm of lip, neoplasm of lip (diagnosis), lip neoplasm, Lip Neoplasms [Disease/Finding], lips neoplasm, lip tumor, lip tumors, Lip neoplasm NOS, Lips--Tumors, Lip neoplasm, Tumor of lip, Tumour of lip, Neoplasm of lip (disorder), Neoplasm of lip, Lip Neoplasm, Lip Tumor, Neoplasm of Lip, Neoplasm of the Lip, Tumor of Lip, Tumor of the Lip
Italian Tumore delle labbra, Tumore delle labbra non specificato, Neoplasie del labbro
Dutch lipneoplasma NAO, lipneoplasma, Liptumor, Liptumoren, Tumor, lip-, Tumoren, lip-
French Tumeur de la lèvre SAI, Tumeur de la lèvre, Tumeurs de la lèvre, Tumeurs des lèvres, Tumeurs labiales
German Neubildung an der Lippe NNB, Neubildung an der Lippe, Lippentumoren, Tumoren, Lippen-
Portuguese Neoplasia do lábio NE, Neoplasia do lábio, Neoplasias Labiais
Spanish Neoplasia en labio NEOM, neoplasia de labio (trastorno), neoplasia de labio, tumor de labio, Neoplasia en labio, Neoplasias de los Labios
Japanese 口唇新生物NOS, コウシンシンセイブツ, コウシンシンセイブツNOS, 口唇腫瘍, 口唇新生物
Swedish Läpptumörer
Finnish Huulen kasvaimet
Czech Novotvar rtu, Novotvar rtu NOS, ret - nádory, nádory rtu
Polish Nowotwory warg
Hungarian Ajak neoplasia, Ajak neoplasia k.m.n.
Norwegian Leppeneoplasmer, Leppetumorer, Leppesvulster

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Definition (NCI) A malignant epithelial neoplasm arising from the lips.
Concepts Neoplastic Process (T191)
SnomedCT 154435005, 187599002, 269515006
English carcinoma of lip (diagnosis), carcinoma of lip, lip neoplasm malignant carcinoma, carcinomas lip, lip carcinoma, carcinoma lip, Carcinoma of lip, Carcinoma of lip (disorder), Lip Carcinoma, Carcinoma of Lip, Carcinoma of the Lip
Spanish carcinoma de labio (trastorno), carcinoma de labio

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Definition (NCI) A primary or metastatic malignant neoplasm involving the lip.
Concepts Neoplastic Process (T191)
MSH D008048
ICD9 140
ICD10 C00 , C00.9
SnomedCT 93869001, 187599002, 309808004, 187625008, 363348004
English Malignant neoplasm of lip, Lip, unspecified, Malignant neoplasm of lip, unspecified, Malignant neoplasm lip, unsp, malignant neoplasm of lip (diagnosis), lip neoplasm malignant, malignant neoplasm of lip, Malignant lip cancer, Malignant lip neoplasm, Cancer of the Lip, Cancers, Lip, Lip Cancer, Lip Cancers, cancer of lip, cancer lips, lip cancer, lip cancers, of lip cancer, cancer of the lip, cancer lip, Cancer, Lip, Malignant neoplasm of lip, unspecified (disorder), Lips--Cancer, CA - Cancer of lip, Cancer of lip, Malignant tumor of lip, Malignant tumour of lip, Malignant tumor of lip (disorder), Malignant neoplasm of lip, NOS, Malignant Lip Neoplasm, Malignant Lip Tumor, Malignant Neoplasm of Lip, Malignant Neoplasm of the Lip, Malignant Tumor of Lip, Malignant Tumor of the Lip, Cancer of Lip
Dutch maligne lipkanker, kanker van de lip, maligne lipneoplasma, maligne neoplasma van de lip, Maligne neoplasma van lip, niet gespecificeerd, Maligne neoplasma van lip, Lipkanker, Tumor van de lip
French Cancer malin de la lèvre, Cancer de la lèvre, Cancer labial, Tumeur labiale maligne, Tumeur maligne de la lèvre
German boesartiger Lippenkrebs, boesartige Neubildung der Lippe, boesartige Lippenneubildung, Krebs der Lippe, Boesartige Neubildung der Lippe, Boesartige Neubildung: Lippe, nicht naeher bezeichnet, Lippenkrebs
Italian Tumore maligno delle labbra, Tumore maligno del labbro, Cancro del labbro
Portuguese Neoplasia maligna do lábio, Cancro do lábio, Câncer dos Lábios, Câncer Labial
Spanish Cáncer de labio, Neoplasia maligna de labio, Cáncer de Labio, cáncer de labio, no especificado, neoplasia maligna de labio, no especificada, neoplasia maligna de labio, no especificada (trastorno), neoplasia maligna de labio (trastorno), Malignant neoplasm of lip, unspecified, neoplasia maligna de labio, cáncer del labio, tumor maligno del labio (trastorno), tumor maligno del labio, Cáncer Labial
Japanese 口唇の悪性新生物, 口唇癌, 口唇悪性新生物, 悪性口唇癌, コウシンガン, アクセイコウシンガン, コウシンノアクセイシンセイブツ, コウシンアクセイシンセイブツ
Czech Maligní novotvar rtu, Maligní nádor rtu, Nádor rtu, ret - rakovina, rakovina rtu
Korean 입술의 상세불명 악성신생물, 입술의 악성신생물
Hungarian Malignus ajakrák, Malignus ajakdaganatok, Ajakrák, Malignus ajakdaganat
Norwegian Leppekreft

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Definition (NCI) A basal cell carcinoma arising from the lip.
Concepts Neoplastic Process (T191)
Dutch lipbasaalcelcarcinoom
French Carcinome basocellulaire de la lèvre
German Basalzellenkarzinom an der Lippe
Italian Carcinoma a cellule basali delle labbra
Portuguese Basalioma do lábio
Spanish Carcinoma basocelular de labio
Japanese 口唇基底細胞癌, コウシンキテイサイボウガン
Czech Bazocelulární karcinom rtu
English Lip basal cell carcinoma, basal carcinoma cell lip, lip basal cell carcinoma, basal cell carcinoma, lip, Lip Basal Cell Carcinoma, Basal Cell Carcinoma of Lip, Basal Cell Carcinoma of the Lip
Hungarian Ajak basalsejtes carcinomája

Ontology: Squamous cell carcinoma of lip (C0280302)

Definition (NCI) A squamous cell carcinoma that arises from the lip. It affects males more often than females and it usually involves the lower lip. Risk factors include UV exposure, alcohol consumption, smoking, and immunosuppression.
Concepts Neoplastic Process (T191)
SnomedCT 255071008
English SCC-Squamous cell carcinom lip, squamous cell carcinoma of lip, lip neoplasm malignant carcinoma squamous cell, squamous cell carcinoma of lip (diagnosis), Lip squamous cell carcinoma, SCC - Squamous cell carcinoma of lip, Squamous cell carcinoma of lip, Squamous cell carcinoma of lip (disorder), Lip SCC, Lip Squamous Cell Carcinoma, SCC of Lip, SCC of the Lip, Squamous Cell Carcinoma of Lip, Squamous Cell Carcinoma of the Lip
Czech Karcinom šupinatých buněk rtů
Dutch lip squameuscelcarcinoom
French Carcinome épidermoïde de la lèvre
German Plattenepithelkarzinom der Lippe
Hungarian Ajak squamosus-sejtes carcinomája
Italian Carcinoma a cellule squamose delle labbra
Japanese 口唇扁平上皮癌, コウシンヘンペイジョウヒガン
Portuguese Carcinoma pavimentocelular do lábio
Spanish Carcinoma labial de células escamosas, carcinoma de células escamosas de labio (trastorno), carcinoma de células escamosas de labio