II. Epidemiology

  1. Most common in 40 to 50 year old women

III. Pathophysiology

  1. Neuroendocrine tumor arising from from glomus bodies
    1. Jugular bulb origin or
    2. Middle ear neural plexus
  2. Tympanic Membrane invasion follows Hearing Loss
  3. May involve Cranial Nerves

IV. Symptoms

V. Signs

  1. Dark blue, purple or red-blue mass behind TM

VI. Diagnosis

VII. Differential Diagnosis

  1. Anomalous Carotid Artery
  2. Anomalous jugular bulb

VIII. Management

  1. Do not biopsy (very vascular)
  2. Surgical excision

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Related Studies

Ontology: Glomus Tumor (C0017653)

Definition (NCI) A rare benign or malignant mesenchymal neoplasm arising from cells that resemble the modified smooth muscle cells of the glomus body. The majority of glomus tumors occur in the distal extremities.
Definition (MSH) A blue-red, extremely painful vascular neoplasm involving a glomeriform arteriovenous anastomosis (glomus body), which may be found anywhere in the skin, most often in the distal portion of the fingers and toes, especially beneath the nail. It is composed of specialized pericytes (sometimes termed glomus cells), usually in single encapsulated nodular masses which may be several millimeters in diameter (From Stedman, 27th ed). CHEMODECTOMA, a tumor of NEURAL CREST origin, is also sometimes called a glomus tumor.
Concepts Neoplastic Process (T191)
MSH D005918
ICD10 M8711/0
SnomedCT 189193002, 393567008, 10438002, 403969002
English Glomus Tumors, Tumor, Glomus, Tumors, Glomus, Glomus Tumor, Glomus Tumor [Disease/Finding], tumor glomus, glomus tumor, glomus tumour, glomus tumors, Glomus tumour (disorder), Glomus tumor, Glomus tumour, Glomus tumor (disorder), Glomus tumor (morphologic abnormality), Glomus Neoplasm
Dutch glomus tumor, glomustumor, Gezwel, glomus-, Glomusgezwel
French Tumeur du glomus, Tumeur glomique, Angiomyoneurome
German Glomus Tumor, Glomustumor
Spanish Tumor glómico, tumor glómico (anomalía morfológica), tumor glómico (trastorno), tumor glómico, Glomangioma, Tumor Glómico
Japanese グロームス腫瘍, グロームスシュヨウ
Swedish Nysttumör
Czech glomangiom, Glomus tumor
Finnish Glomuskasvain
Polish Guz kłębka skórnego, Kłębczak
Hungarian Glomus tumor
Italian Tumore del glomo, Tumore glomico
Norwegian Glomussvulst, Glomustumor
Portuguese Tumor glómico, Tumor Glômico

Ontology: Extra-Adrenal Paraganglioma (C0030422)

Definition (MSH) A relatively rare, usually benign neoplasm originating in the chemoreceptor tissue of the CAROTID BODY; GLOMUS JUGULARE; GLOMUS TYMPANICUM; AORTIC BODIES; and the female genital tract. It consists histologically of rounded or ovoid hyperchromatic cells that tend to be grouped in an alveolus-like pattern within a scant to moderate amount of fibrous stroma and a few large thin-walled vascular channels. (From Stedman, 27th ed)
Definition (NCI) A benign or malignant paraganglioma arising from sympathetic or parasympathetic paraganglia outside the adrenal gland.
Concepts Neoplastic Process (T191)
MSH D010236
ICD10 M8693/1
SnomedCT 189744003, 134298001, 302834008, 51747000
English Chemodectoma, Nonchromaffin Paragangliomas, Paraganglioma, Nonchromaffin, Paragangliomas, Nonchromaffin, Paraganglioma, Non-Chromaffin, Paraganglioma, Extra-Adrenal, Extra-Adrenal Paragangliomas, Non-Chromaffin Paraganglioma, Non-Chromaffin Paragangliomas, Paraganglioma, Extra Adrenal, Paraganglioma, Non Chromaffin, Paragangliomas, Extra-Adrenal, Paragangliomas, Non-Chromaffin, Nonchromaffin Paraganglioma, Extra-adrenal paraganglioma, NOS, Extra-Adrenal Paraganglionic Neoplasm, Extra-Adrenal Paraganglioma, PARAGANGLIOMAS, FAMILIAL NONCHROMAFFIN, 1, CHEMODECTOMAS, [M]Extra-adrenal paragangl.NOS, [M]Extra-adrenal paraganglioma, NOS, Extra-adrenal paragangl.NOS, Paraganglioma, Extra-Adrenal [Disease/Finding], Extra-adrenal paraganglioma NOS, chemodectoma, Paragangliomas, Familial Nonchromaffin, 1, Chemodectomas, [M]Chemodectoma, [M] (Extra-adrenal paraganglioma, NOS) or (chemodectoma), [M] (Extra-adrenal paraganglioma, NOS) or (chemodectoma) (disorder), [M]Extra-adrenal paraganglioma, NOS (morphologic abnormality), extra-adrenal paraganglioma, extra-adrenal paraganglioma (diagnosis), neoplasm of paraganglioma extra-adrenal, Extra-adrenal paraganglioma, Nonchromaffin paraganglioma, Non-chromaffin paraganglioma, Extra-adrenal paraganglioma (disorder), Extra-adrenal paraganglioma (morphologic abnormality), Nonchromaffin paraganglioma, NOS, Extraadrenal Paraganglioma
Japanese 非クロム親和性傍神経細胞腫, ヒクロムシンワセイボウシンケイサイボウシュ, 化学感受体腫, 傍神経節腫-非クロム親和性, ケモデクトーマ, 副腎外パラガングリオーマ, 非クロム親和性パラガングリオーマ, 非クロム親和性傍神経節腫, パラガングリオーマ-副腎外, パラガングリオーマ-非クロム親和性, 傍神経節腫-副腎外, 副腎外傍神経節腫
Swedish Paragangliom, extraadrenalt
Czech paragangliom nechromafinní, chemodektom, Chemodektom
Finnish Ekstra-adrenaalinen paragangliooma
Italian Paraganglioma non cromaffine, Chemodectoma, Paraganglioma extra adrenale
Croatian Not Translated[Paraganglioma, Extra-Adrenal]
Spanish paraganglioma extrasuprarrenal (trastorno), paraganglioma extrasuprarenal (trastorno), paraganglioma extrasuprarenal, paraganglioma extradrenal, paraganglioma extrasuprarrenal (anomalía morfológica), paraganglioma extrasuprarrenal, paraganglioma no cromafín, quemodectoma, Quimiodectoma, Paraganglioma Extraadrenal, Paraganglioma no Cromafínico, Quemodectoma
Polish Przyzwojak nienadnerczowy, Przyzwojak pozanadnerczowy, Przyzwojak niechromochłonny
Hungarian Chemodectoma
Norwegian Ekstraadrenalt paragangliom
Portuguese Paraganglioma não Cromafim, Paraganglioma Extrassuprarrenal, Paraganglioma não Cromafínico, Quimiodectoma
Dutch chemodectoom, Chemodectoma, Paraganglioma, extra-adrenaal, Paraganglioma, non-chroomaffien, extra-adrenaal paraganglioma
French Paragangliome non chromaffine, Paragangliome extra-surrénalien, Chémodectome, Paragangliome extrasurrénalien
German Chemodektom, Paragangliom, extraadrenales, Paragangliom, nichtchromaffines