II. Precautions
- Systemic Glucocorticoids have significant adverse effects (see below)
- Systemic Glucocorticoids have many established indications with significant efficacy
- Asthma Exacerbation
- COPD Exacerbation
- Stress Dose Steroids
- Cancer Chemotherapy
- Peritonsillar Abscess
- Bells Palsy
- Acute Gout (in those unable to take NSAIDs)
- Extensive Allergic Contact Dermatitis (>20% of body surface area such as Rhus Dermatitis)
- However, many systemic steroid uses are NOT recommended (esp. for Upper Respiratory Infection) due to evidence against
- Not recommended in Acute Bronchitis (aside from acute COPD or Asthma Exacerbation)
- Not recommended in mild to moderate Acute Pharyngitis (aside from Peritonsillar Abscess)
- Not recommended in Acute Sinusitis
- Not recommended in Allergic Rhinitis (use Inhaled Corticosteroids instead)
- Not recommended in Carpal Tunnel Syndrome (use Carpal Tunnel Corticosteroid Injection instead)
- Controversial in Lumbar Radiculopathy (mixed study results)
III. Dosing: Adult
- Betamethasone (Celestone) 0.5 to 0.9 mg IM/PO qd
- Cortisone (Cortone) 25-300 mg PO qd
- Dexamethasone (Decadron)
- Antiinflammatory: 0.5-9 mg/day PO/IM/IV divided every 6-12 hours
- Hydrocortisone (Cortef)
- See Stress Dose Steroid
- Parenteral: 100 to 150 mg IV/IM q2-6 hours prn
- Oral: 20 to 240 mg/day PO in divided dosing
- Methylprednisolone
- Parenteral (Solu-Medrol) 10 to 125 mg IV/IM
- Oral (Medrol) 4 to 48 mg PO qd
- Medrol Dose pack: tapers from 24 to 0 PO over 7 days
- Avoid medrol dose pack (replace with Prednisone 30 mg orally daily for 5 days would have similar effect)
- Triamcinolone (Aristocort, Kenalog) 4 to 48 mg PO/IM qd
- Prednisolone (Prelone) 5-60 mg PO/IV/IM orally daily
- Requires no first pass metabolism via the liver (unlike Prednisone)
- Prednisone (Deltasone) 5-60 mg orally daily
- Requires first pass metabolism through the liver, but has 1:1 bioavailablity in most cases
- Consider Prednisolone in severe liver disease
- Rayos (delayed release version of Prednisone)
- Marketed to reduce morning inflammation in Rheumatoid Arthritis
- Taken at 10 pm with intended release starting at 2 am
- Unlikely to add significant benefit for the cost (more than $200 for thirty 5 mg tabs)
- (2012) Prescr Lett 19(12): 69
IV. Dosing: Child
- Methylprednisolone (Solu-Medrol)
- Dose: 1-2 mg/kg/dose PO/IV/IM q6h up to 125 mg/dose
- Prednisolone (Prelone)
- Dose: 1-2 mg/kg/dose PO qd to bid up to 60 mg/day
- Maximum: 60 mg per day
- Preparations
- Syrup: 15 mg/5 ml
- Liquid: 5 mg/5 ml
- Dexamethasone
- Asthma Exacerbation: 0.3 to 0.6 mg/kg/day up to 10-15 mg for 1-2 days
- Croup: 0.15 to 0.6 mg/kg once up to 10 mg
V. Agents: Overall potency (equivalent dosages)
- High potency
- Betamethasone 0.6 to 0.75 mg
- Dexamethasone 0.75 mg
- Medium potency
- Methylprednisolone 4 mg
- Triamcinolone 4 mg
- Prednisolone 5 mg
- Prednisone 5 mg
- Low potency
- Hydrocortisone 20 mg
- Cortisone 25 mg
VI. Agents: Relative anti-inflammatory potency
- High anti-inflammatory potency
- Betamethasone 20-30
- Dexamethasone 20-30
- Medium anti-inflammatory potency
- Methylprednisolone 5
- Triamcinolone 5
- Prednisolone 4
- Prednisone 4
- Low anti-inflammatory potency
- Hydrocortisone 1
- Cortisone 0.8
VII. Agents: Relative Mineralocorticoid Potency
- Mineralocorticoid Activity
- Cortisone 2
- Hydrocortisone 2
- Prednisolone 1
- Prednisone 1
- No Mineralocorticoid Activity
- Betamethasone
- Dexamethasone
- Methylprednisolone
- Triamcinolone
VIII. Agents: Half Life
- Long half-life (36-54 hours)
- Betamethasone
- Dexamethasone (~56 hours)
- Medium half-life (18-36 hours)
- Methylprednisolone
- Prednisolone (~36 hours)
- Prednisone (~36 hours)
- Triamcinolone
- Short half-life (8-12 hours)
- Cortisone
- Hydrocortisone
IX. Adverse Effects (typically with Long-term Corticosteroid use)
- See Precautions above
- See Prevention below
- Even short course Corticosteroids are associated with increased serious adverse effects
- Fracture (RR 1.9, NNH 140)
- Venous Thromboembolism (RR 3.3, NNH 454)
- Sepsis (RR 5.3, NNH 1250)
- Waljee (2017) BMJ 12:357 +PMID: 28404617 [PubMed]
- Corticosteroid Associated Osteoporosis
- Corticosteroid Myopathy
- Motor restlessness
- Sleep disturbance
- Hypertension
- Iatrogenic Diabetes Mellitus (or acute worsening of Diabetes Mellitus control including Diabetic Ketoacidosis)
- Hyperlipidemia
- Fluid retention
- Immune Suppression
- Avascular Necrosis (e.g. Osteonecrosis of the hip)
- May occur even after single, short-term low dose course
- Dilisio (2014) Orthopedics 37(7):e631-6 +PMID: 24992058 [PubMed]
- Corticosteroid Induced Adrenal Insufficiency
- Typically does not occur if Prednisone 20 mg equivalent used <2-3 weeks
- Tapering is generally not required for shorter steroid courses (and raises total steroid dose)
- Cardiovascular disease risk
- Psychiatric effects
- Includes depression, anxiety, mania, Psychosis, Delirium and Insomnia
- Typically occurs in first week of therapy and resolves within a week of stopping the Corticosteroid
- Most have mild to moderate symptoms but may be severe in up to 5% of cases
- Symptoms may also occur (uncommonly) with high potency Topical Corticosteroids, Intranasal Corticosteroids
- Incidence of psychiatric effects increases with dose
- Occurs in 1% of patients on Prednisone 40 mg orally daily or less
- Occurs in 5% of patients on Prednisone 40 mg to 80 mg orally daily or less
- Occurs in 18% of patients on Prednisone 80 mg orally daily or more
- References
- (2014) Presc Lett 21(12):69-70
X. Prevention: Corticosteroid complications
- See Corticosteroid Associated Osteoporosis
- See Steroid-Induced Hyperglycemia
- Avoid use when not truly indicated (e.g. Sinusitis, Acute Bronchitis, Pharyngitis)
- See Precautions above
- Even short course Corticosteroids (1 week) are associated with increased risk of Fractures, VTE and Sepsis
- (2017) Presc Lett 24(7)
- Waljee (2017) BMJ 357:j1415 +PMID:28404617 [PubMed]
XI. References
- Swadron and Hope in Herbert (2018) EM:Rap 18(9):16-8
- Dvorin (2020) Am Fam Physician 101(2): 89-94 [PubMed]
- Lane (1998) Endocrinol Metab Clin North Am 27:465-83 [PubMed]
Images: Related links to external sites (from Bing)
Related Studies
| Dexamethasone (on 6/18/2017 at Walmart.com) | ||
| Dexamethasone 0.5mg | #30 tablets for $4.00 | $0.13 each |
| Dexamethasone 0.5mg | #90 tablets for $10.00 | $0.11 each |
| Dexamethasone 0.75mg | #12 tablets for $4.00 | $0.33 each |
| Dexamethasone 0.75mg | #36 tablets for $10.00 | $0.28 each |
| Dexamethasone 4mg | #6 tablets for $4.00 | $0.67 each |
| Dexamethasone 4mg | #18 tablets for $10.00 | $0.56 each |
| Hydrocortisone (on 6/18/2017 at Walmart.com) | ||
| Hydrocortisone 1% cream (28.35-30g tube) | #1 tube for $4.00 | $4.00 each |
| Hydrocortisone 1% cream (28.35-30g tube) | #3 tubes for $10.00 | $3.33 each |
| Hydrocortisone 2.5% cream (30gm tube) | #1 tube for $4.00 | $4.00 each |
| Hydrocortisone 2.5% cream (30gm tube) | #3 tubes for $10.00 | $3.33 each |
| Prednisone (on 6/18/2017 at Walmart.com) | ||
| Prednisone 2.5mg | #30 tablets for $4.00 | $0.13 each |
| Prednisone 2.5mg | #90 tablets for $10.00 | $0.11 each |
| Prednisone 5mg | #30 tablets for $4.00 | $0.13 each |
| Prednisone 5mg | #90 tablets for $10.00 | $0.11 each |
| betamethasone (on 5/17/2017 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| BETAMETHASONE AC-SP 6 MG/ML VL | Generic | $6.23 per ml |
| BETAMETHASONE DP 0.05% CRM | Generic | $1.91 per gram |
| BETAMETHASONE DP 0.05% LOT | Generic | $0.57 per ml |
| BETAMETHASONE DP 0.05% OINT | Generic | $2.76 per gram |
| BETAMETHASONE DP AUG 0.05% CRM | Generic | $0.39 per gram |
| BETAMETHASONE DP AUG 0.05% LOT | Generic | $2.17 per ml |
| BETAMETHASONE DP AUG 0.05% OIN | Generic | $2.41 per gram |
| BETAMETHASONE VA 0.1% CREAM | Generic | $1.05 per gram |
| BETAMETHASONE VA 0.1% LOTION | Generic | $0.73 per ml |
| BETAMETHASONE VALER 0.1% OINTM | Generic | $0.80 per gram |
| BETAMETHASONE VALER 0.12% FOAM | Generic | $5.10 per gram |
| dexamethasone (on 5/17/2017 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| DEXAMETHASONE 0.1% EYE DROP | Generic | $9.34 per ml |
| DEXAMETHASONE 0.5 MG TABLET | Generic | $0.05 each |
| DEXAMETHASONE 0.5 MG/5 ML ELX | Generic | $0.13 per ml |
| DEXAMETHASONE 0.5 MG/5 ML LIQ | Generic | $0.19 per ml |
| DEXAMETHASONE 0.75 MG TABLET | Generic | $0.09 each |
| DEXAMETHASONE 1 MG TABLET | Generic | $0.25 each |
| DEXAMETHASONE 1.5 MG TABLET | Generic | $0.08 each |
| DEXAMETHASONE 120 MG/30 ML VL | Generic | $0.92 per ml |
| DEXAMETHASONE 2 MG TABLET | Generic | $0.47 each |
| DEXAMETHASONE 4 MG TABLET | Generic | $0.11 each |
| DEXAMETHASONE 4 MG/ML VIAL | Generic | $0.77 per ml |
| DEXAMETHASONE 6 MG TABLET | Generic | $0.40 each |
| DEXAMETHASONE INTENSOL 1 MG/1 ML | Generic | $0.77 per ml |
| hydrocortisone (on 6/14/2017 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| HYDROCORTISONE 0.5% CREAM | Generic OTC | $0.09 per gram |
| HYDROCORTISONE 0.5% OINTMENT | Generic OTC | $0.12 per gram |
| HYDROCORTISONE 1% CREAM | Generic | $0.06 per gram |
| HYDROCORTISONE 1% LOTION | Generic OTC | $0.07 per ml |
| HYDROCORTISONE 1% OINTMENT | Generic | $0.18 per gram |
| HYDROCORTISONE 10 MG TABLET | Generic | $0.29 each |
| HYDROCORTISONE 100 MG/60 ML | Generic | $0.09 per ml |
| HYDROCORTISONE 2.5% CREAM | Generic | $0.13 per gram |
| HYDROCORTISONE 2.5% LOTION | Generic | $0.19 per ml |
| HYDROCORTISONE 2.5% OINTMENT | Generic | $0.10 per gram |
| HYDROCORTISONE 20 MG TABLET | Generic | $0.47 each |
| HYDROCORTISONE 5 MG TABLET | Generic | $0.18 each |
| HYDROCORTISONE BUTY 0.1% CREAM | Generic | $3.03 per gram |
| HYDROCORTISONE BUTYR 0.1% OINT | Generic | $2.44 per gram |
| HYDROCORTISONE BUTYR 0.1% SOLN | Generic | $2.60 per ml |
| HYDROCORTISONE PLUS 1% CREAM | Generic OTC | $0.06 per gram |
| HYDROCORTISONE VAL 0.2% CREAM | Generic | $2.90 per gram |
| HYDROCORTISONE VAL 0.2% OINTMT | Generic | $4.60 per gram |
| HYDROCORTISONE-ALOE 1% CREAM | Generic OTC | $0.07 per gram |
| methylprednisolone (on 5/17/2017 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| METHYLPREDNISOLONE 16 MG TAB | Generic | $2.48 each |
| METHYLPREDNISOLONE 4 MG DOSEPK | Generic | $0.41 each |
| METHYLPREDNISOLONE 4 MG TABLET | Generic | $0.68 each |
| METHYLPREDNISOLONE 8 MG TAB | Generic | $1.44 each |
| prednisolone (on 5/17/2017 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| PREDNISOLONE 15 MG/5 ML SOLN | Generic | $0.05 per ml |
| PREDNISOLONE 15 MG/5 ML SYRUP | Generic | $0.05 per ml |
| PREDNISOLONE 5 MG/5 ML SOLN | Generic | $0.59 per ml |
| PREDNISOLONE AC 1% EYE DROP | Generic | $7.17 per ml |
| PREDNISOLONE ODT 10 MG TABLET | Generic | $10.41 each |
| PREDNISOLONE SOD 1% EYE DROP | Generic | $5.09 per ml |
| PREDNISOLONE SOD PH 25 MG/5 ML | Generic | $1.02 per ml |
| prednisone (on 5/17/2017 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| PREDNISONE 1 MG TABLET | Generic | $0.13 each |
| PREDNISONE 10 MG TAB DOSE PACK | Generic | $0.85 each |
| PREDNISONE 10 MG TABLET | Generic | $0.12 each |
| PREDNISONE 2.5 MG TABLET | Generic | $0.11 each |
| PREDNISONE 20 MG TABLET | Generic | $0.14 each |
| PREDNISONE 5 MG TAB DOSE PACK | Generic | $0.56 each |
| PREDNISONE 5 MG TABLET | Generic | $0.11 each |
| PREDNISONE 5 MG/5 ML SOLUTION | Generic | $0.23 per ml |
| PREDNISONE 5 MG/ML SOLUTION | Generic | $1.56 per ml |
| PREDNISONE 50 MG TABLET | Generic | $0.25 each |
Ontology: Adrenal Cortex Hormones (C0001617)
| Definition (NCI) | Hormones synthesized in the cortex of the adrenal gland and consist of two subclasses, glucocorticoids (carbohydrate regulation) and mineralocorticoids (electrolyte regulation). |
| Definition (NCI_NCI-GLOSS) | Any steroid hormone made in the adrenal cortex (the outer part of the adrenal gland). They are also made in the laboratory. Corticosteroids have many different effects in the body, and are used to treat many different conditions. They may be used as hormone replacement, to suppress the immune system, and to treat some side effects of cancer and its treatment. Corticosteroids are also used to treat certain lymphomas and lymphoid leukemias. |
| Definition (CSP) | any of the 21-carbon steroids elaborated by the adrenal cortex (excluding the sex hormones of adrenal origin) in response to adrenocorticotropic hormone (ACTH) released by the pituitary gland or to angiotensin II; called also adrenocorticoid, corticoid, adrenal cortical or adrenocortical steroid, and adrenocortical or cortical hormone. |
| Concepts | Pharmacologic Substance (T121) , Hormone (T125) , Steroid (T110) |
| MSH | D000305 |
| SnomedCT | 320476006, 332333008, 79440004, 21568003 |
| LNC | LP20687-7, LP31653-6 |
| English | Corticoids, Corticosteroids, Hormones, Adrenal Cortex, Corticosteroids [resp], Corticosteroids [skin], Corticosteroids [respiratory use], adrenal cortex hormone, Adrenal Cortex Hormones [Chemical/Ingredient], Adrenal cortex hormones, adrenal cortex hormones, corticosteroids, adrenal corticosteroids, adrenal cortical hormone, adrenal corticosteroid, adrenocorticosteroids, corticoid, corticoids, Adrenal Cortex Hormones, Corticosteroids [respiratory use] (product), Corticosteroids [skin] (product), Adrenal cortical hormone, Adrenocorticosteroids, Corticoid preparation (product), Corticoid preparation, Adrenal cortical hormone (substance), corticosteroid, Adrenal cortical hormone, NOS, Corticoid preparation, NOS, Corticoid preparation (substance), Corticosteroids [respiratory use] (substance), Corticosteroids [skin] (substance), Adrenal Cortex Steroids, Corticosteroid, Therapeutic Corticosteroid |
| Swedish | Binjurebarkshormoner |
| Czech | hormony kůry nadledvin, kortikosteroidy, kortikoidy |
| Finnish | Lisämunuaiskuoren hormonit |
| French | Hormones cortico-surrénaliennes, Corticoïdes, Corticostéroïdes, Hormones corticosurrénaliennes |
| Italian | Corticoidi, Corticosteroidi, Ormoni corticosurrenali |
| Russian | NADPOCHECHNIKOV KORY GORMONY, KORTIKOSTEROIDY, KORTIKOIDY, КОРТИКОИДЫ, КОРТИКОСТЕРОИДЫ, НАДПОЧЕЧНИКОВ КОРЫ ГОРМОНЫ |
| Spanish | corticoides (producto), preparado con corticoides (producto), corticoides, preparado con corticoides, Corticoesteroides, corticosteroide [uso respiratorio] (producto), corticosteroide (uso dermatológico), corticosteroide (uso dermatológico) (producto), corticosteroide [uso respiratorio], Corticosteroides, adrenocorticoesteroide, corticosteroides (piel) (producto), corticosteroides (piel), corticosteroides [uso respiratorio] (producto), corticosteroides [uso respiratorio], hormona de la corteza suprarrenal, hormona suprarrenal cortical (sustancia), hormona suprarrenal cortical, preparado de corticoides (producto), preparado de corticoides (sustancia), preparado de corticoides, Corticoides, Hormonas de la Corteza Suprarrenal |
| Croatian | KORTIKOSTEROIDI |
| Polish | Hormony kory nadnerczy, Kortykoidy, Kortykosteroidy |
| Japanese | コルチコイド, 副腎皮質ホルモン, コルチコステロイド, ステロイドホルモン-副腎皮質, 副腎皮質ステロイド |
| Norwegian | Binyrebarkhormoner, Kortikosteroider, Kortikoider |
| Portuguese | Corticosteroides, Corticoides, Hormônios do Córtex Suprarrenal, Corticoesteroides |
| German | Corticoide, Corticosteroide, Nebennierenrindenhormone |
Ontology: Betamethasone (C0005308)
| Definition (NCI) | A synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory activities. Betamethasone binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions. |
| Definition (MSH) | A glucocorticoid given orally, parenterally, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. Its lack of mineralocorticoid properties makes betamethasone particularly suitable for treating cerebral edema and congenital adrenal hyperplasia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p724) |
| Definition (PDQ) | A synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory activities. Betamethasone binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39273&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39273&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C303" NCI Thesaurus) |
| Concepts | Pharmacologic Substance (T121) , Steroid (T110) , Hormone (T125) |
| MSH | D001623 |
| SnomedCT | 116571008, 29896003 |
| LNC | LP35866-0, MTHU017343 |
| English | Betadexamethasone, Betamethasone, Flubenisolone, Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11beta,16beta)-, betamethasone (medication), Betamethasone [Chemical/Ingredient], BETAMETHASONE, betamethasone, Betamethasone preparation, Flubenisolone preparation, Betamethasone (substance), Betamethasone preparation (product), Betamethasone preparation (substance) |
| Swedish | Betametason |
| Czech | betamethason |
| Finnish | Beetametasoni |
| Italian | Betadesametasone, Flubenisolone, Betametasone |
| Russian | BETADEKSAMETAZON, BETAMETAZON, FLUBENIZOLON, БЕТАДЕКСАМЕТАЗОН, БЕТАМЕТАЗОН, ФЛУБЕНИЗОЛОН |
| Spanish | preparado de betametasona (producto), betametasona (producto), preparado de flubenisolona, preparado de betametasona, betametasona (sustancia), betametasona, preparado de betametasona (sustancia), Betadexametasona, Betametasona, Flubenisolona |
| Polish | Flubenisolonum, Betametazon |
| Japanese | フルベニソロン, ベタメタゾン, ベタデキサメタゾン |
| French | Bétaméthasone |
| German | Betadexamethason, Betamethason, Flubenisolon |
| Portuguese | Betadexametasona, Betametasona, Flubenisolona |
Ontology: Cortisone (C0010137)
| Definition (NCI_NCI-GLOSS) | A natural steroid hormone produced in the adrenal gland. It can also be made in the laboratory. Cortisone reduces swelling and can suppress immune responses. |
| Definition (NCI) | A corticosteroid with potent glucocorticoid activity. Therapeutic cortisone is the inactive precursor molecule of the active hormone cortisol, which is the hydroxylation product of cortisone by 11-beta-steroid dehydrogenase. Cortisol increases blood pressure and blood sugar levels, and suppresses the immune system, therefore cortisone is used to treat allergies or inflammation. |
| Definition (NCI) | A steroid hormone synthesized and secreted by the adrenal gland and necessary for life. It is involved with maintaining cardiovascular function, blood glucose balance, regulating the inflammatory response and metabolism of proteins, carbohydrates, and fat. |
| Definition (MSH) | A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to the active metabolite HYDROCORTISONE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726) |
| Definition (CSP) | naturally occurring glucocorticoid used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent; cortisone itself is inactive and is converted in the liver to the active metabolite cortisol. |
| Concepts | Pharmacologic Substance (T121) , Hormone (T125) , Steroid (T110) |
| MSH | D003348 |
| SnomedCT | 32498003, 111150008 |
| LNC | LP18544-4, LP157319-7, MTHU004611 |
| English | cortisone, Pregn-4-ene-3,11,20-trione, 17,21-dihydroxy-, 17,21-Dihydroxypregn-4-ene-3,11,20-trione, Cortisone, Cortisone [Chemical/Ingredient], cortisones, CORTISONE, Compound E, Cortisone preparation, Cortisone (substance), Cortisone preparation (product), Cortisone product, CORT, Cortisone preparation (substance), Therapeutic Cortisone |
| Swedish | Kortison |
| Czech | kortison |
| Finnish | Kortisoni |
| Russian | KORTIZON, КОРТИЗОН |
| Japanese | コルチゾン, 11-デヒドロ-17-ヒドロキシコルチコステロン |
| Spanish | preparado con cortisona (producto), cortisona (producto), preparado con cortisona, cortisona (sustancia), cortisona, preparado de cortisona (producto), preparado de cortisona (sustancia), preparado de cortisona, Cortisona |
| Croatian | KORTIZON |
| Polish | Kortyzon |
| Norwegian | Kortison |
| French | Cortisone |
| German | Cortison |
| Italian | Cortisone |
| Portuguese | Cortisona |
Ontology: Dexamethasone (C0011777)
| Definition (CHV) | a kind of steroid drug |
| Definition (CHV) | a kind of steroid drug |
| Definition (NCI) | A synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexamethasone also interferes with NF-kB activation and apoptotic pathways. This agent lacks the salt-retaining properties of other related adrenal hormones. (NCI04) |
| Definition (NCI_NCI-GLOSS) | A synthetic steroid (similar to steroid hormones produced naturally in the adrenal gland). Dexamethasone is used to treat leukemia and lymphoma and may be used to treat some of the problems caused by other cancers and their treatment. |
| Definition (CSP) | anti-inflammatory 9-fluoro-glucocorticoid. |
| Definition (MSH) | An anti-inflammatory 9-fluoro-glucocorticoid. |
| Definition (PSY) | A synthetic analogue of cortisol. |
| Definition (PDQ) | A synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexamethasone also interferes with NF-kB activation and apoptotic pathways. This agent lacks the salt-retaining properties of other related adrenal hormones. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39789&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39789&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C422" NCI Thesaurus) |
| Concepts | Pharmacologic Substance (T121) , Steroid (T110) |
| MSH | D003907 |
| SnomedCT | 325354000, 116568000, 372584003, 7561000 |
| LNC | LP32530-5, LP18549-3, MTHU004621 |
| English | Dexamethasone, Hexadecadrol, Methylfluorprednisolone, Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11beta,16alpha)-, 1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone, 9Alpha-fluoro-11beta,17alpha,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione, 9Alpha-fluoro-16alpha-methylprednisolone, 9alpha-Fluoro-16alpha- methylprednisolone, Fluoro-9alpha Methyl-16alpha Prednisolone, (11Beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 16Alpha-methyl-9alpha-fluoro-1,4-pregnadiene-11beta,17alpha,21-triol-3,20-dione, 16Alpha-methyl-9alpha-fluoro-delta1-hydrocortisone, 16Alpha-methyl-9alpha-fluoroprednisolone, dexamethasone, Dexamethasonum, Desamethasone, Dexamethasone [endocrine use], DEXAMETHASONE, dexamethasone (medication), Dexamethasone [Chemical/Ingredient], dexamethasone (DMX), Dexamethasone (product), Dexamethasone [endocrine use] (product), Dexamethasone preparation, Dexamethasone (substance), Dexamethasone preparation (product), DXM, DM, Dexamethasone [endocrine use] (substance), Dexamethasone preparation (substance) |
| Swedish | Dexametason |
| Czech | dexamethason |
| Finnish | Deksametasoni |
| Russian | DEKSAMETAZON, GEKSADEKADROL, ГЕКСАДЕКАДРОЛ, ДЕКСАМЕТАЗОН |
| Japanese | コルソン, デキサA, デキサメサゾン, ダブM, デカドロン, ビスオDS, ミタゾーン, オイラゾンD, デカドロンN, デキサ･チョーセイ, デキサ･ママレット, デキサメ, ヘキサデカドロール, デルゾン, サンテゾーン, デキサルチン, フルメプレドニゾロン, マキシデックス, デキサメタゾン, エースミン |
| Spanish | preparado con dexametasona (producto), dexametasona (producto), preparado con dexametasona, dexametasona (uso endocrino), dexametasona (uso endocrino) (producto), dexametasona (sustancia), dexametasona, preparado de dexametasona (producto), preparado de dexametasona (sustancia), preparado de dexametasona, Dexametasona, Hexadecadrol |
| Italian | Metil-fluoro-prednisolone, Esadecadrol, Desametasone |
| Croatian | DEKSAMETAZON |
| Polish | Deksametazon |
| Norwegian | Dexametason |
| French | Dexaméthasone |
| German | Dexamethason, Hexadecadrol |
| Portuguese | Dexametasona, Hexadecadrol |
Ontology: Glucocorticoids (C0017710)
| Definition (NCI_NCI-GLOSS) | A compound that belongs to the family of compounds called corticosteroids (steroids). Glucocorticoids affect metabolism and have anti-inflammatory and immunosuppressive effects. They may be naturally produced (hormones) or synthetic (drugs). |
| Definition (NCI) | Synthetically derived forms of the naturally occurring Glucocorticoids. |
| Definition (NCI) | A group of corticosteroids that affect carbohydrate metabolism (gluconeogenesis, liver glycogen deposition, elevation of blood sugar), inhibit corticotropin secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system. (MSH2002_06_01) |
| Definition (PSY) | Any steroid-like compound capable of significantly influencing intermediary metabolism. Glucocorticoids are also clinically useful anti-inflammatory agents. |
| Definition (CSP) | group of corticosteroids that affect carbohydrate metabolism, inhibit corticotropin secretion, and possess pronounced anti-inflammatory activity; they also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system. |
| Definition (MSH) | A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system. |
| Concepts | Hormone (T125) , Steroid (T110) |
| MSH | D005938 |
| SnomedCT | 255653002, 35150008, 116596006, 419933005 |
| LNC | LP31487-9 |
| Spanish | glucocorticoide (sustancia), glucocorticoide, preparado de glucocorticoides (producto), glucocorticoides, glucocorticoides (producto), preparado de glucocorticoides, glucocorticoide (producto), Efecto Glucocorticoide, hormona glucocorticoide (sustancia), hormona glucocorticoide, preparado de glucocorticoides (sustancia), Glucocorticoides |
| German | Glukokortikosteroide, Glukokortikoide, Glucocorticoide |
| Swedish | Glukokortikoider |
| English | GLUCOCORTICOIDS, [HS051] GLUCOCORTICOIDS, Glucocorticoids [Chemical/Ingredient], glucocorticoids hormone, glucocorticoid hormone, glucocorticoid hormones, glucocorticoids, Glucocorticoids, Glucocorticoid (product), Glucocorticoid hormone, Glucocorticoid hormone (substance), Glucocorticoid preparation (product), Glucocorticoid preparation, glucocorticoid, Glucocorticoid preparation (substance), Therapeutic Glucocorticoid, Glucocorticoid, Glucocorticoid (substance) |
| Czech | glukokortikoidy |
| Finnish | Glukokortikoidit |
| Russian | GIDROKSIKORTIKOSTEROIDY SINTETICHESKIE, GLIUKOKORTIKOIDOV ANALOGI, GLIUKOKORTIKOIDY SINTETICHESKIE, 17-GIDROKSIKORTIKOSTEROIDY SINTETICHESKIE, 11-GIDROKSIKORTIKOSTEROIDY SINTETICHESKIE, 17-GIDROKSIKORTIKOSTEROIDOV ANALOGI, GLIUKOKORTIKOIDY, 11-GIDROKSIKORTIKOSTEROIDOV ANALOGI, ГЛЮКОКОРТИКОИДЫ, ГЛЮКОКОРТИКОИДЫ СИНТЕТИЧЕСКИЕ, 11-ГИДРОКСИКОРТИКОСТЕРОИДОВ АНАЛОГИ, 11-ГИДРОКСИКОРТИКОСТЕРОИДЫ СИНТЕТИЧЕСКИЕ, 17-ГИДРОКСИКОРТИКОСТЕРОИДОВ АНАЛОГИ, 17-ГИДРОКСИКОРТИКОСТЕРОИДЫ СИНТЕТИЧЕСКИЕ, ГИДРОКСИКОРТИКОСТЕРОИДЫ СИНТЕТИЧЕСКИЕ, ГЛЮКОКОРТИКОИДОВ АНАЛОГИ |
| Croatian | GLUKOKORTIKOIDI |
| Polish | Glikokortykosteroidy |
| Norwegian | Glukokortikoider |
| Portuguese | Glucocorticoides, Glicocorticoides, Efeito Glucocorticoide |
| French | Glucocorticoïdes, Glucocorticostéroïdes |
| Italian | Glucocorticoidi |
Ontology: Hydrocortisone (C0020268)
| Definition (MSHCZE) | Nejdůležitější glukokortikoid vylučuje NADLEDVINOVÁ KŮRA. Jeho syntetický analog se užívá ve formě injekce nebo lokálně při léčbě zánětů, alergií, kolagenóz, astmatu, adrenokortikální nedostatečnosti, šoku a někdy při nádorových onemocněních. |
| Definition (NCI) | A synthetic or semisynthetic analog of natural hydrocortisone hormone produced by the adrenal glands with primary glucocorticoid and minor mineralocorticoid effects. As a glucocorticoid receptor agonist, hydrocortisone promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppresses immune and inflammatory responses. (NCI04) |
| Definition (NCI_NCI-GLOSS) | A hormone made by the adrenal cortex (the outer layer of the adrenal gland). It helps the body use glucose (a sugar), protein, and fats. Cortisol made in the laboratory is called hydrocortisone. It is used to treat many conditions, including inflammation, allergies, and some cancers. Cortisol is a type of glucocorticoid hormone. |
| Definition (NCI_NCI-GLOSS) | A drug used to relieve the symptoms of certain hormone shortages and to suppress an immune response. |
| Definition (MSH) | The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions. |
| Definition (CSP) | main glucocorticoid secreted by the adrenal cortex; its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions. |
| Definition (PDQ) | A synthetic or semisynthetic analog of natural hydrocortisone hormone produced by the adrenal glands with primary glucocorticoid and minor mineralocorticoid effects. As a glucocorticoid receptor agonist, hydrocortisone promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppresses immune and inflammatory responses. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39274&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39274&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C555" NCI Thesaurus) |
| Concepts | Pharmacologic Substance (T121) , Steroid (T110) , Hormone (T125) |
| MSH | D006854 |
| SnomedCT | 396458002, 56423005, 16602005 |
| LNC | LP97871-5, LP70288-3, LP14161-1, MTHU001562, MTHU035101 |
| English | Compound F, Cortisol, Hydrocortisone, Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-, Dihydrocortisone, (11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione, hydrocortisone, Domolene, Therapeutic Hydrocortisone, hydrocortisone (medication), HYDROCORTISONE, Hydrocortisone [Chemical/Ingredient], cortisols, 17-hydroxycorticosterone, hydrocortisones, Cortisol (substance), Compound F preparation, Cortisol preparation, Cortisol product, HC - Hydrocortisone, Hydrocortisone preparation, Hydrocortisone product, Hydrocortisone (substance), Hydrocortisone preparation (product), cortisol, HC, Hydrocortisone preparation (substance) |
| Swedish | Hydrokortison |
| Spanish | cortisol, preparado con hidrocortisona (producto), hidrocortisona (producto), preparado con hidrocortisona, cortisol (sustancia), hidrocortisona (sustancia), hidrocortisona, preparado de hidrocortisona (producto), preparado de hidrocortisona (sustancia), preparado de hidrocortisona, Cortisol, Hidrocortisona |
| Czech | hydrokortison, kortisol, kortizol, hydrokortizon |
| Finnish | Kortisoli |
| Russian | KORTIZOL, GIDROKORTIZON, ГИДРОКОРТИЗОН, КОРТИЗОЛ |
| Japanese | コルチソール, ヒドロコルチゾン, コルチソル, 17-ヒドロキシコルチコステロン, ハイドロコルチゾン, コートリル, コルチゾール |
| Italian | Cortisolo, Idrocortisone |
| Croatian | HIDROKORTIZON |
| Polish | Hydrokortyzon, Kortyzol |
| Norwegian | Kortisol, Hydrokortison |
| French | Cortisol, Hydrocortisone |
| German | Cortisol, Hydrocortison, Kortisol |
| Portuguese | Cortisol, Hidrocortisona |
Ontology: Methylprednisolone (C0025815)
| Definition (CHV) | a kind of steroidal anti-inflammatory drugs |
| Definition (NCI) | A synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone binds to and activates specific nuclear receptors, resulting in altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cell populations. |
| Definition (NCI_NCI-GLOSS) | A corticosteroid hormone replacement. |
| Definition (MSH) | A PREDNISOLONE derivative with similar anti-inflammatory action. |
| Definition (CSP) | synthetic glucocorticoid derived from progesterone, used in replacement therapy for adrenal insufficiency and as an anti-inflammatory and immunosuppressant. |
| Definition (PDQ) | A synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone binds to and activates specific nuclear receptors, resulting in altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cell populations. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=41528&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=41528&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C647" NCI Thesaurus) |
| Concepts | Pharmacologic Substance (T121) , Steroid (T110) , Hormone (T125) |
| MSH | D008775 |
| SnomedCT | 325387001, 116593003, 27242001 |
| LNC | LP18584-0, MTHU004699 |
| English | 6 Methylprednisolone, 6-Methylprednisolone, Methylprednisolone, Metipred, Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-6-methyl-, (6alpha,11beta)-, Methylprednisolone [endoc], 6Alpha-Methylprednisolone, (6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione, methylprednisolone, Methylprednisolonum, Methylprednisolone [endocrine use], methylprednisolone (medication), METHYLPREDNISOLONE, Methylprednisolone [Chemical/Ingredient], methylPREDNISolone, Methylprednisolone [endocrine use] (product), 6-alpha-Methylprednisolone preparation, Methylprednisolone preparation, Methylprednisolone (substance), Methylprednisolone preparation (product), MePRDL, Methylprednisolone [endocrine use] (substance), Methylprednisolone preparation (substance), MethylPREDNISolone |
| Swedish | Metylprednisolon |
| Czech | methylprednisolon |
| Finnish | Metyyliprednisoloni |
| Russian | METILPREDNIZOLON, METIPRED, URBAZON, МЕТИЛПРЕДНИЗОЛОН, МЕТИПРЕД, УРБАЗОН |
| Japanese | メドロール, メチルプレドニゾロン, メチルプレドニソロン, ウルバソン |
| Spanish | preparado con 6-alfa-metilprednisolona, preparado con metilprednisolona (producto), metilprednisolona (producto), preparado con metilprednisolona, metilprednisolona (uso endocrino), metilprednisolona (uso endocrino) (producto), metilprednisolona (sustancia), metilprednisolona, preparado de 6-alfa-metilprednisolona, preparado de metilprednisolona (producto), preparado de metilprednisolona (sustancia), preparado de metilprednisolona, Metilprednisolona |
| French | 6-Méthylprednisolone, Méthylprednisolone |
| Croatian | METILPREDNISOLON |
| Polish | Metyloprednizolon |
| German | Methylprednisolon |
| Italian | Metilprednisolone |
| Portuguese | Metilprednisolona |
Ontology: prednisolone (C0032950)
| Definition (NCI) | A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisolone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations. (NCI04) |
| Definition (NCI_NCI-GLOSS) | A drug that lessens inflammation and suppresses the body's immune response. It may also kill cancer cells. Prednisolone is used to treat disorders in many organ systems and to treat the symptoms of several types of leukemia and lymphoma. It is also being studied in the treatment of other types of cancer. Prednisolone is a type of therapeutic glucocorticoid. |
| Definition (MSH) | A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states. |
| Definition (CSP) | synthetic glucocorticoid with the general properties of the corticosteroids. |
| Definition (PDQ) | A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisolone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43296&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43296&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C769" NCI Thesaurus) |
| Concepts | Pharmacologic Substance (T121) , Steroid (T110) |
| MSH | D011239 |
| SnomedCT | 317418003, 325425005, 116601002, 52388000 |
| LNC | LP18169-0, MTHU003522 |
| English | Prednisolone, Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-, Prednisolone [for preparations see rectal prednisolone], Prednisolone [see rectal pred], 1,2-Dehydrohydrocortisone, (11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione, Metacortandralone, Delta(1)Hydrocortisone, Delta-F, Delta1-dehydro-hydrocortisone, Prednisolonum, Prednisolone [endocrine use], prednisolone (medication), PREDNISOLONE, Prednisolone [Chemical/Ingredient], prednisoLONE, Prednisolone [for preparations see rectal prednisolone] (product), Prednisolone [endocrine use] (product), .delta.1-Hydrocortisone, Deltahydrocortisone, Deltahydrocortisone preparation, Metacortandralone preparation, Prednisolone preparation, Prednisolone product, Prednisolone (substance), Prednisolone preparation (product), PRDL, Prednisolone [endocrine use] (substance), Prednisolone [for preparations see rectal prednisolone] (substance), Prednisolone preparation (substance), prednisolone, PrednisoLONE |
| Swedish | Prednisolon |
| Czech | prednisolon, depersolon |
| Finnish | Prednisoloni |
| Russian | DEPERZOLON, PREDNIZOLON, ДЕПЕРЗОЛОН, ПРЕДНИЗОЛОН |
| Japanese | プレドニソロン, デルポPD, ドニソロン, プレドニン, シエリゾロン, プレドニゾロン |
| Spanish | preparado con metacortandralona, preparado con prednisolona (producto), prednisolona (producto), preparado con deltahidrocortisona, preparado con prednisolona, prednisolona (uso endocrino), prednisolona (para preparaciones ver prednisolona rectal), prednisolona (uso endocrino) (producto), prednisolona (para preparaciones ver prednisolona rectal) (producto), prednisolona (sustancia), prednisolona, preparado de deltahidrocortisona, preparado de metacortandralona, preparado de prednisolona (producto), preparado de prednisolona (sustancia), preparado de prednisolona, Prednisolona |
| Croatian | PREDNIZOLON |
| Polish | Encortolon, Prednizolon |
| French | Prednisolone |
| German | Prednisolon |
| Italian | Prednisolone |
| Portuguese | Prednisolona |
Ontology: Prednisone (C0032952)
| Definition (NCI_NCI-GLOSS) | A drug used to lessen inflammation and lower the body's immune response. It is used with other drugs to treat leukemia and lymphoma and other types of cancer. It is also used alone or with other drugs to prevent or treat many other conditions. These include conditions related to cancer, such as anemia (a low level of red blood cells), allergic reactions, and loss of appetite. Prednisone is a type of therapeutic glucocorticoid. |
| Definition (NCI) | A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cell populations. |
| Definition (MSH) | A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver. |
| Definition (CSP) | synthetic anti-inflammatory glucocorticoid derived from cortisone; biologically inert and converted to prednisolone in the liver. |
| Definition (PDQ) | A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42487&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42487&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C770" NCI Thesaurus) |
| Concepts | Pharmacologic Substance (T121) , Hormone (T125) , Steroid (T110) |
| MSH | D011241 |
| SnomedCT | 116602009, 10312003 |
| LNC | LP18109-6, MTHU003245 |
| English | Dehydrocortisone, delta-Cortisone, Pregna-1,4-diene-3,11,20-trione, 17,21-dihydroxy-, 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione, Deltadehydrocortisone, 1;2-Dehydrocortisone, Delta(1)-Cortisone, Deltacortisone, Prednisonum, Metacortandracin, prednisone, prednisone (medication), PREDNISONE, 1,2-Dehydrocortisone, Prednisone [Chemical/Ingredient], Delta 1-Cortisone, predniSONE, .delta.1-Cortisone, 1, 2-Dehydrocortisone, Deltacortisone preparation, Deltadehydrocortisone preparation, Prednisone preparation, Prednisone (substance), Prednisone preparation (product), PRD, Prednisone, Prednisone preparation (substance), PRED, PredniSONE |
| Swedish | Prednison |
| Czech | prednison |
| Finnish | Prednisoni |
| Russian | PREDNIZON, DEL'TA-KORTIZON, DEGIDROKORTIZON, ДЕГИДРОКОРТИЗОН, ДЕЛЬТА-КОРТИЗОН, ПРЕДНИЗОН |
| Spanish | deltacortisona, prednisona (producto), preparado con prednisona (producto), preparado con deltacortisona, deltadehidrocortisona, preparado con deltadehidrocortisona, preparado con prednisona, prednisona (sustancia), prednisona, preparado de deltacortisona, preparado de deltadehidrocortisona, preparado de prednisona (producto), preparado de prednisona (sustancia), preparado de prednisona, delta Cortisona, Deshidrocortisona, Prednisona |
| Italian | Deidrocortisone, delta-Cortisone, Prednisone |
| Croatian | PREDNIZON |
| Polish | Prednizon, Encorton |
| Japanese | デヒドロコルチゾン, プレドニソン, プレドニゾン |
| French | Prednisone |
| German | Dehydrocortison, Prednison, Delta-Cortison |
| Portuguese | delta-Cortisona, Desidrocortisona, Prednisona |
Ontology: Glucocorticoids, Systemic (C3540777)
| Concepts | Steroid (T110) , Pharmacologic Substance (T121) , Hormone (T125) |
| English | Glucocorticoids, Glucocorticoids, Systemic |
