II. Epidemiology

  1. Most common Diabetic Neuropathy
  2. Accounts for 26% of diabetic Peripheral Neuropathy

III. Symptoms

  1. Distal Paresthesias, hyperesthesias or numbness
  2. Symptoms worse at night
  3. "Stocking & Glove" Neuropathy
    1. Related to longest axons affected first
  4. Muscle Weakness and atrophy may be noted
  5. Painful Peripheral Neuropathy occurs in a subset of diabetic Peripheral Neuropathy (20%)
    1. Pain due to light stroking (dynamic mechanical Allodynia)
    2. Increased Temperature sensitivity (thermal hyperalgesia)
    3. Pain attacks

IV. Signs: Specific nerve functions affected

  1. Vibration and position sense
    1. Achilles and Patellar tendon Deep Tendon Reflexes
    2. Gait Ataxia
  2. Sharp-dull discrimination
  3. Two Point Discrimination
  4. Decreased "protective Sensation"
    1. 10 g Monofilament Test
  5. Muscle Strength may also be affected

V. Differential Diagnosis

VI. Management

  1. See Diabetic Peripheral Neuropathy

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Related Studies

Ontology: Diabetic distal sensorimotor polyneuropathy (C0393832)

Concepts Disease or Syndrome (T047)
SnomedCT 230573007
English Diabet dist snsorimotr polyneu, Diabetic distal sensorimotor polyneuropathy, Diabetic distal sensorimotor polyneuropathy (disorder)
Spanish polineuropatía sensorimotriz distal diabética (trastorno), polineuropatía sensorimotriz distal diabética