II. Prevention

  1. Sunscreen
    1. SPF 15 daily, starting in childhood
    2. SPF 30 during spring and summer
  2. Tobacco Cessation

III. Management: General Measures

  1. Maintain hydration
  2. Tobacco Cessation
  3. Frequent Skin Lubricant use

IV. Management: Topical Agents

  1. Retinoid
    1. Tretinoin (Retinoic Acid, Vitamin A Acid, Retin A) starting at 0.025% Cream 1-2 times per week qhs (may use OTC)
    2. Adapalene (Differin)
    3. See Retin A for adverse effects
      1. Must wear Sunscreen daily
  2. Alpha-Hydroxy acids (Lac-Hydrin 12%) or Urea 3-6%
    1. Combine with Skin Lubricant

V. Management: Other Adjuncts

  1. Estrogen Replacement Therapy
  2. Topical Estrogen
  3. Antioxidants and other additives
    1. Vitamin C (questionable efficacy)
    2. Vitamin E
    3. Hyaluronic acid

VI. Management: Skin Cosmetic Procedure

  1. See Skin Cosmetic Procedure
  2. Chemical Peels
  3. Derm Abrasion
  4. Laser Abrasion

VII. Management: Avoid Ineffective Measures for Wrinkles and Skin Damage

  1. Green Tea
  2. Coenzyme Q10
  3. Niacinamide

VIII. References

  1. (2021) Presc Lett 28(1): 4-5

Images: Related links to external sites (from Bing)

Related Studies

Ontology: Skin Aging (C0037271)

Definition (MEDLINEPLUS)

Your skin changes as you age. You might notice wrinkles, age spots and dryness. Your skin also becomes thinner and loses fat, making it less plump and smooth. It might take longer to heal, too.

Sunlight is a major cause of skin aging. You can protect yourself by staying out of the sun when it is strongest, using sunscreen with an SPF of 15 or higher, wearing protective clothing, and avoiding sunlamps and tanning beds. Cigarette smoking also contributes to wrinkles. The wrinkling increases with the amount of cigarettes and number of years a person has smoked.

Many products claim to revitalize aging skin or reduce wrinkles, but the Food and Drug Administration has approved only a few for sun-damaged or aging skin. Various treatments soothe dry skin and reduce the appearance of age spots.

NIH: National Institute on Aging

Definition (MSH) The process of aging due to changes in the structure and elasticity of the skin over time. It may be a part of physiological aging or it may be due to the effects of ultraviolet radiation, usually through exposure to sunlight.
Concepts Organ or Tissue Function (T042)
MSH D015595
SnomedCT 26065007
English Aging, Skin, Photoaging of Skin, Skin Aging, Solar Aging of Skin, Skin aging, function, aging skin, skin ageing, ags skin, skin aging, ageing skin, age skin, skin age, aged skin, aging skins, skin photoaging, Aging Skin, Skin--Aging, Skin aging, Skin ageing, Skin aging, function (observable entity), Skin aging (function)
Swedish Hudens åldrande
Finnish Ihon ikääntyminen
French Vieillissement de la peau, Héliodermie, Vieillissement cutané par exposition au soleil, Photovieillissement de la peau, Vieillissement de la peau par le soleil, Photovieillissement cutané, Vieillissement cutané, Vieillissement cutané par exposition aux UV
Japanese 老化-皮膚, 皮膚のしわ, 光加齢-皮膚, 皮膚の日光加齢, 皮膚の光加齢, 日光加齢-皮膚, 皮膚老化,
Italian Fotoinvecchiamento della pelle, Invecchiamento della pelle
Polish Starzenie się skóry, Zmarszczki, Marszczenie się skóry
Czech stárnutí kůže, stárnutí kůže vlivem slunečního záření, kůže - stárnutí
Spanish envejecimiento cutáneo, envejecimiento de la piel (entidad observable), envejecimiento de la piel (función), envejecimiento de la piel, Envejecimiento de la Piel, Envejecimiento Solar de la Piel, Fotoenvejecimiento de la Piel
German Hautalterung, Lichtbedingtes Hautaltern, Sonnenbedingtes Hautaltern
Dutch Aan zonlicht gerelateerde huidveroudering, Huidveroudering, Veroudering, huid-
Portuguese Envelhecimento da Pele, Envelhecimento Solar da Pele, Fotoenvelhecimento da Pele

Ontology: Wrinkled face (C0262478)

Concepts Finding (T033)
SnomedCT 248194004
English Facial wrinkling, face lines, facial wrinkles, face wrinkling, wrinkled face, face line, Facial wrinkles, Lined face, Wrinkled face, Wrinkled face (finding)
Spanish cara arrugada (hallazgo), cara arrugada

Ontology: Photodamaged skin (C1698818)

Concepts Disease or Syndrome (T047)
Dutch door licht geschadigde huid
French Peau photolésée
German lichtgeschaedigte Haut
Italian Pelle fotodanneggiata
Portuguese Pele foto-lesada
Spanish Fotolesión cutánea
Japanese 光線性皮膚障害, コウセンセイヒフショウガイ
Czech Světlem poškozená kůže
Hungarian Fénykárosodott bőr
English Photodamaged skin