II. Definition

  1. Ventricular enlargement AND
  2. Normal left ventricular wall thickness AND
  3. Systolic Dysfunction

III. Epidemiology

  1. Prevalence: 1 in 2500
    1. Leading cause of Heart Transplantation in the United States
  2. Onset age 40-59 years old

IV. Pathophysiology

  1. Familial (Autosomal Dominant) in 25-35% of cases

V. Causes

VI. Findings

VII. Diagnostics

  1. Echocardiogram
    1. First-line study in suspected Cardiomyopathy
  2. Electrocardiogram (EKG)
    1. Septal Q Waves
    2. Bundle Branch Block
    3. Tachyarrhythmia

VIII. Management

IX. Complications

  1. Arrhythmias
  2. Thromboembolic events

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Ontology: Cardiomyopathy, Dilated (C0007193)

Definition (NCI) Cardiomyopathy which is characterized by dilation and contractile dysfunction of the left and right ventricles. It may be idiopathic, or it may result from a myocardial infarction, myocardial infection, or alcohol abuse. It is a cause of congestive heart failure.
Definition (MSH) A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein.
Concepts Disease or Syndrome (T047)
MSH D002311
ICD10 I42.0
SnomedCT 74368002, 195018001, 389995008, 399020009, 195021004
English Cardiomyopathies, Dilated, Dilated Cardiomyopathies, Dilated Cardiomyopathy, COCM - Congestive cardiomyop, Cardiomyopathy, Dilated, CCM - Congestive cardiomyopath, Cardiomyopathy, dilated, dilated cardiomyopathy (diagnosis), congestive cardiomyopathy, congestive cardiomyopathy (diagnosis), dilated cardiomyopathy, COCM Congestive (dilated) cardiomyopathy, Congestive (dilated) cardiomyopathy, Cardiomyopathy, Dilated [Disease/Finding], Cardiomyopathy;congestive, cardiomyopathy dilated, primary dilated cardiomyopathy, cardiomyopathy congestive, Dilated cardiomyopathy, Congestive cardiomyopathy, Congestive Cardiomyopathy, Primary dilated cardiomyopathy, COCM - Congestive cardiomyopathy, DCM - Dilated cardiomyopathy, Congestive dilated cardiomyopathy, CCM - Congestive cardiomyopathy, Congestive cardiomyopathy (disorder), Primary dilated cardiomyopathy (disorder), cardiomyopathy; cardiomyopathy, dilated, heart; dilatation, cardiomyopathy, Cardiomyopathy, congestive
Italian Cardiomiopatia congestizia, Cardiomiopatia congestizia (dilatativa), Cardiomiopatia congestizia (dilatativa) cronica, Cardiomiopatia dilatativa, Miocardiopatia congestizia
Dutch congestieve (verwijde) cardiomyopathie, congestieve COCM (verwijde) cardiomyopathie, gedilateerde cardiomyopathie, cardiomyopathie; hartdilatatie, hart; dilatatie, cardiomyopathie, Cardiomyopathie met hartdilatatie (niet-obstructief), congestieve cardiomyopathie, Cardiomyopathie met hartdilatatie, Cardiomyopathie, congestieve, Congestieve cardiomyopathie, Dilatatiecardiomyopathie
French Cardiomyopathie (dilatée) congestive, CMD (CardioMyopathie Dilatée), Cardiomyopathie congestive, Cardiomyopathie non obstructive, Myocardiopathie non obstructive, Cardiomyopathie dilatée
German kongestive (dilatative) Kardiomyopathie, COGM kongestive (dilatative) Kardiomyopathie, dilatative Kardiomyopathie, Kardiomyopathie, kongestive, Kardiomyopathie, dilatative, kongestive Kardiomyopathie, Dilatative Kardiomyopathie, Kongestive Kardiomyopathie
Portuguese Miocardiopatia congestiva (dilatada), Miocardiopatia dilatada, Miocardiopatia Dilatada, Cardiomiopatia Dilatada, Cardiomiopatia congestiva
Spanish Cardiomiopatía congestiva (dilatada), Cardiomiopatía dilatada, Cardiomiopatía Dilatada, Miocardiopatía Dilatada, miocardiopatía congestiva dilatada, miocardiopatía congestiva (trastorno), miocardiopatía congestiva, miocardiopatía congénita (trastorno), miocardiopatía congénita, miocardiopatía dilatada primaria (trastorno), miocardiopatía dilatada primaria, Cardiomiopatía congestiva
Japanese うっ血性(拡張型)心筋症, ウッケツセイカクチョウガタシンキンショウ, カクチョウガタシンキンショウ, ウッケツセイシンキンショウ, うっ血型心筋症, 心筋症-拡張型, うっ血性心筋症, うっ血性心筋障害, 心筋症-鬱血性, 拡張型心筋症, 鬱血性心筋症, 心筋症-うっ血性, 拡張性心筋症, 欝血型心筋症, 欝血性心筋症, 鬱血型心筋症
Swedish Kardiomyopati, dilaterande
Czech kardiomyopatie kongestivní, Kongestivní kardiomyopatie, Kongestivní (dilatační) kardiomyopatie, Dilatační kardiomyopatie, Kongestivní (dilatační) kardiomyopatie DKMP, DKMP, dilatační kardiomyopatie, kardiomyopatie dilatační
Finnish Dilatoiva kardiomyopatia
Korean 확장성 심장근육병증
Polish Kardiomiopatia rozstrzeniowa, Kardiomiopatia przekrwienna
Hungarian COCM pangásos (dilatált) cardiomyopathia, Dilatált cardiomyopathia, Pangásos (dilatált) cardiomyopathia, Congestiv cardiomyopathia
Norwegian Dilatert kardiomyopati