Rheumatology Book

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Spondyloarthropathy

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  1. Clinical Features: Common to every spondyloarthropathy
    1. Inflammatory back pain
    2. Dactylitis
      1. Inflammation of entire digit
    3. Enthesitis
      1. Inflammation of tendon and ligament bony attachments
      2. Common areas of involvement
        1. Achilles tendon insertion (calcaneus)
        2. Platar fascia insertion (calcaneus)
        3. Patellar tendon insertion (tibial tubercle)
        4. Patella margin (superior and inferior)
        5. Metatarsal heads
        6. Spinal ligament insertion (vertebral body)
  2. Causes
    1. Ankylosing Spondylitis
    2. Reactive Arthritis (e.g. Reiter's Syndrome)
    3. Psoriatic Arthritis
    4. Inflammatory Bowel Disease with Spondyloarthropathy
  3. Differential Diagnosis
    1. Rheumatoid Arthritis
  4. Labs
    1. Rheumatoid Factor (RF) negative
    2. Erythrocyte Sedimentation Rate (ESR) elevated
    3. C-Reactive Protein (CRP) elevated
    4. Complete Blood Count (CBC)
    5. Anemia of Chronic Disease
    6. HLA-B27 positive
    7. Synovial Fluid exam: WBCs > 2,000/ml
  5. References
    1. Liu in Noble (2001) Primary Care, p. 1280-93
    2. Kataria (2004) Am Fam Physician 69:2853

Spondylarthropathies (C0949691)

Definition (MSH)Heterogeneous group of arthritic diseases sharing clinical and radiologic features and presence of the HLA-B27 ANTIGEN.
Definition (CSP)group of related inflammatory, arthritic diseases of the joints in the spine sharing clinical and radiologic features and are associated with the MHC class I molecule HLA-B27 antigen.
ConceptsDisease or Syndrome (T047)
ICD9721.90
MSHD025242
EnglishBECHTEREW SYNDROME, Disorder of joint of spine, MARIE-STRUMPELL SPONDYLITIS, SPDA1, Spondarthropathy, Spondylarthropathies, Spondylarthropathy, Spondylarthrosis, spondyloarthropathy
Spanishespondiloartropatia, trastorno de articulacion de la columna vertebral
Parent ConceptsSpondylosis (C0038019), Arthritis (C0003864), Spinal Diseases (C0037933), Spondylarthritis (C0949690), Arthropathies NOS (C0022408), Ambiguous concept (C1274012)
SourcesAOD, CSP, MSH, MTH, MTHICD9, OMIM, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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