Hypertrophic Osteoarthropathy

Aka: Hypertrophic Osteoarthropathy, Osteoarthropathy, Acropachy

advertisement

II. Definition

  1. Excess skin and bone proliferation at distal extremity

III. Pathophysiology

  1. Large Platelets accumulate in distal extremities
  2. Fibroblast growth factors released
  3. Results in edema and excess Collagen deposition
  4. Increased bone formation distally also occurs

IV. Causes

  1. See Hypertrophic Osteoarthropathy Causes

V. Symptoms

  1. Often asymptomatic
  2. Deep bone pain at distal extremities (usually legs)

VI. Signs

  1. Digital Clubbing
  2. Bone thickening of wrists and ankles

VII. References

  1. Klippel (1997) Primer Rheumatic Diseases, p. 370-1

Images: Related links to external sites (from Bing)

These images are a random sampling from a Bing search on the term "Hypertrophic Osteoarthropathy." Click on the image (or right click) to open the source website in a new browser window. Search Bing for all related images

Related Studies

Related Topics in Bone Disorders

advertisement