Nephrology Book

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Hypokalemia due to Renal Potassium Loss

Aka: Hypokalemia due to Renal Potassium Loss, Renal Potassium Loss
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  1. Definition
    1. Hypokalemia with Urine Potassium > 20 meq/day
  2. Blood Pressure Elevated
    1. Renin Elevated
      1. Malignant Hypertension
      2. Renovascular disease
      3. Renin secreting tumor
    2. Renin Normal
      1. Liddle's Syndrome
    3. Renin Low
      1. Aldosterone High
        1. Primary Hyperaldosteronism
        2. Bilateral adrenal hyperplasia
        3. Dexamethasone suppression
      2. Aldosterone Low
        1. Mineralocorticoid ingestion
        2. Congenital Adrenal Hyperplasia
        3. Cushing's Syndrome
        4. Ectopic ACTH
        5. Tobacco chewing
        6. Licorice
  3. Blood Pressure Normal
    1. Serum Bicarbonate Low
      1. Renal Tubular Acidosis
    2. Serum Bicarbonate High
      1. Urine Chloride Low (<10 meq/L)
        1. Vomiting
      2. Urine Chloride High (>10 meq/L)
        1. Barter's Syndrome
        2. Normotensive primary Hyperaldosteronism
        3. Diuretic use
        4. Severe potassium depletion

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