Mental Health Book

http://www.fpnotebook.com/

Lithium CarbonateAka: Lithium, Eskalith, Lithobid

Advertisement

  1. Indication
    1. Bipolar Disorder
  2. Pharmacokinetics
    1. Steady state reached in 5 days
    2. Therapeutic Trough levels
      1. Acute mania: 1.0 to 1.5 meq/liter
      2. Maintenance Bipolar Disorder: 0.6 to 1.2 meq/liter
    3. Increasing dose 300 mg/day raises level 0.2 meq/liter
  3. Dosing
    1. Start: 300 mg PO bid
    2. Effective dose: 900 to 1800 mg per day divided bid
  4. Adverse Effects
    1. Tremor
    2. Polydipsia
    3. Hypothyroidism
    4. Weight gain
    5. Nausea or Vomiting
    6. Diarrhea
  5. Toxicity
    1. Cerebellar Signs or symptoms
    2. Mechanism
      1. Poor therapeutic window
      2. Renal excretion
  6. Drug Interactions
    1. Diuretics
    2. NSAIDs
    3. ACE Inhibitors
  7. Monitoring
    1. Renal Function tests
    2. Thyroid Function Tests

Lithium (C0023870)

Definition (MSH)An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight 6.94. Salts of lithium are used in treating BIPOLAR DISORDER.
Definition (CSP)white metal, symbol Li, atomic number 3; lithium salts are used in treating the manic phase of bipolar disorder.
ConceptsPharmacologic Substance (T121) , Element, Ion, or Isotope (T196)
MSHD008094
EnglishLi - Lithium, Li element, Li+ element, Lithium, LITHIUM PREPARATION, Lithium product
Spanishlitio
Parent ConceptsMetals, Alkali (C0025554), Psychotropic Drugs (C0033978), Lithium salt (C0302213), Antidepressive Agents (C0003289), Elements (C0013879), Lithium AND/OR lithium compound (C0303506), Mood stabilizing drug (C1276998), Mood stabilizing agent (C1533054), Bipolar Agents (C1579429)
SourcesAOD, CSP, LCH, LNC, MSH, MTH, NCI, NDFRT, PDQ, RXNORM, SCTSPA, SNOMEDCT, USPMG, VANDF
Derived from the NIH UMLS (Unified Medical Language System)


Lithobid (C0700751)

ConceptsPharmacologic Substance (T121) , Inorganic Chemical (T197)
MSHD016651
EnglishLithobid
SourcesMSH, NCI, PDQ, RXNORM
Derived from the NIH UMLS (Unified Medical Language System)


Eskalith (C0700753)

ConceptsPharmacologic Substance (T121) , Inorganic Chemical (T197)
MSHD016651
EnglishEskalith
SourcesMSH, NCI, PDQ, RXNORM
Derived from the NIH UMLS (Unified Medical Language System)



Navigation Tree