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Desvenlafaxine

Aka: Desvenlafaxine, Pristiq

Efficacy
1. May be less effective than Venlafaxine XR (Effexor XR)
Benefits (compared with Effetypxor XR)
1. Easier to dose (only one dose) but as noted above, this is less effective than Effexor
2. Touted to be better tolerated than Effexor, but studies do not bear this out
3. Effexor XR will be generic in 2010 and is preferred
Dosing
1. Dose: 50 mg orally daily
2. Tapering (do not cut tablet)
  1. Week 1: Skip one dose
  2. Week 2: Skip two doses
  3. Week 3: Skip three doses
  4. Week 4: Stop medication
Adverse Effects
1. Antidepressant Withdrawal
2. Empty ghost capsule in stool (typical finding)
References
1. (2008) Ann Pharmacother 42:1439

Medication Costs
Pristiq (on 2/9/2012 at DrugStore.com)
Pristiq 50mg 24 Hour Tablets	#30 for $150.98	($5.03/unit)
Pristiq 100mg 24 Hour Tablets	#30 for $152.99	($5.10/unit)
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information.

Family Practice Notebook

Patients should address specific medical concerns with their physicians.

Although access to this page is not restricted, the information found here is intended for use by medical providers.

This page was written by Scott Moses, MD, last revised on 4/19/2009 and last published on 5/14/2013.

This is one of 5887 pages in the Family Practice Notebook