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GHB Withdrawal
Aka: GHB Withdrawal, Gamma Hydroxybutyrate Withdrawal
- See Also
- Gamma Hydroxybutyrate
- Chemical Dependency
- Drug Withdrawal
- Pathophysiology
- GHB Dependence is rare due to rapid elimination
- GHB Dependence may occur with excessive use
- Frequent dosing (q1-3 hours around the clock)
- Chronic use
- Symptoms: Withdrawal
- Early symptoms
- Insomnia
- Tremor
- Anxiety
- Confusion
- Nausea and Vomiting
- Later symptoms
- Agitation
- Vivid Hallucinations
- Combative behavior
- Disorientation
- Associated Symptoms: Autonomic Instability
- Tachycardia
- Hypertension
- Tremor
- Diaphoresis
- Differential Diagnosis
- Other Sedative-Hypnotic Use
- Alcohol Withdrawal
- Sympathomimetic intoxication
- Serotonin Syndrome
- Neuroleptic Malignant Syndrome
- Thiamine deficiency
- Thyrotoxicosis
- Pheochromocytoma
- Steroid Psychosis
- Labs
- See Gamma Hydroxybutyrate
- Management
- Agitation may require restraints
- Four point Physical Restraints
- See also Chemical Restraints
- Symptomatic management
- Sedation
- Benzodiazepine
- Barbiturate
- References
- Dyer (2001) Ann Emerg Med 37(2):147-52