II. Indications
- Prevention of Dental Caries in children
- Use when water supply has inadequate fluoride
-
Osteoporosis Prevention
- No longer recommended (previously recommended for adults at risk at 25 mg daily)
III. Precautions
- Narrow Therapeutic Index: Too high dosing effects
- In areas with very high fluoride water concentration:
- Pregnant women and children should use bottled water
IV. Dosing Schedule for children for Dental Caries prevention
- Ages 3 months to 3 years old
- Local Water Fluoride <0.3 ppm: Fluoride 0.25 mg qd
- Local Water Fluoride 0.3-0.7 ppm: No Fluoride
- Local Water Fluoride >0.7 ppm: No Fluoride
- Ages 3 to 6 years old
- Local Water Fluoride <0.3 ppm: Fluoride 0.50 mg qd
- Local Water Fluoride 0.3-0.7 ppm: Fluoride 0.25 mg qd
- Local Water Fluoride >0.7 ppm: No Fluoride Supplement
- Ages 6 to 16 years old
- Local Water Fluoride <0.3 ppm: Fluoride 1.00 mg qd
- Local Water Fluoride 0.3-0.7 ppm: Fluoride 0.50 mg qd
- Local Water Fluoride >0.7 ppm: No Fluoride
V. Efficacy
- Prevents Dental Caries
- Initially thought to prevent osteoporotic Fractures if started early and in low doses
- Found to increase bone density 10% per year
- However resulting bone is not thought to be as strong, and may not confer advantage in Osteoporosis Prevention
VI. Preparations
- Drops: 0.125 mg, 0.25 mg and 0.5 mg per dropper
- Chewable tablets: 0.5 mg, 1 mg
- Tablets: 1 mg
- Multi-Vitamins (Tri-vi-flor and poly-vi-flor)
- Available as drops and chewable tablets
- Write specifically for older, generic formulation (another pharmaceutical switch to re-patent an old drug)
- Fluoride varnish (applied at dental visits, in addition to oral Fluoride Supplementation as needed)
- Fluoride varnish is also applied to teeth at each pediatric dental visits after Tooth Eruption (6 months)
- See Oral Health in Children
- Sievers (2016) Am Fam Physician 93(9):743-4 [PubMed]
VII. References
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Related Studies
| sodium fluoride (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| SODIUM FLUORIDE 0.2% RINSE | Generic | $0.02 per ml |
| SODIUM FLUORIDE 0.25 (0.55) MG | Generic | $0.07 each |
| SODIUM FLUORIDE 0.5 MG(1.1 MG) | Generic | $0.08 each |
| SODIUM FLUORIDE 0.5 MG/ML DROP | Generic | $0.22 per ml |
| SODIUM FLUORIDE 1 MG (2.2 MG) | Generic | $0.07 each |
| SODIUM FLUORIDE 1.1% GEL | Generic | $0.13 per gram |
| SODIUM FLUORIDE 5000 DRY MOUTH | Generic | $0.12 per ml |
| SODIUM FLUORIDE 5000 PLUS CRM | Generic | $0.09 per gram |
| SODIUM FLUORIDE 5000 PPM CREAM | Generic | $0.09 per gram |
| SODIUM FLUORIDE 5000 PPM PASTE | Generic | $0.12 per ml |
| SODIUM FLUORIDE SENSTV 5000PPM | Generic | $0.11 per ml |