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Naproxen
Aka: Naproxen, Naprosyn, Anaprox, Aleve- Class
- NSAID in the propionic acid class
- Pharmacokinetics
- Naproxen sodium has faster action onset than Naproxen
- Dosing
- Naproxen (Naprosyn) 250-500 mg PO bid prn
- Naproxen Sodium (Anaprox, Aleve) 550 mg PO bid prn
- Adverse Effects
- See NSAID Gastrointestinal Adverse Effects
- See NSAID Renal Adverse Effects
- Bleeding risk (inhibits platelet aggregation)
- Naprosyn increases risk almost as much as Aspirin
| Medication Costs | ||
|---|---|---|
| NAPROXEN (on 2/10/2012 at Target.com) | ||
| NAPROXEN 375 MG* Tablet | #30 for $4.00 | ($0.13/unit) |
| NAPROXEN 500 MG* Tablet | #30 for $4.00 | ($0.13/unit) |
| Naproxen (on 2/9/2012 at DrugStore.com) | ||
| Naproxen 125mg/5ml Suspension 500ml Bottle | #1 for $51.49 | ($51.49/unit) |
| Naproxen 250mg Tablets | #90 for $15.99 | ($0.18/unit) |
| Naproxen 375mg Tablets | #90 for $18.99 | ($0.21/unit) |
| Naproxen 500mg Tablets | #60 for $19.99 | ($0.33/unit) |
| Naproxen Sodium (on 2/9/2012 at DrugStore.com) | ||
| Naproxen Sodium 275mg Tablets | #60 for $15.99 | ($0.27/unit) |
| Naproxen Sodium 550mg Tablets | #30 for $14.99 | ($0.50/unit) |
| Naproxen DR (on 2/9/2012 at DrugStore.com) | ||
| Naproxen DR 375mg Enteric Coated Tabs | #60 for $39.99 | ($0.67/unit) |
| Naproxen DR 500mg Enteric Coated Tabs | #60 for $64.99 | ($1.08/unit) |
| Naprosyn (on 2/9/2012 at DrugStore.com) | ||
| Naprosyn 125mg/5ml Suspension | #300 for $54.33 | ($0.18/unit) |
| Naprosyn 375mg Tablets | #100 for $180.71 | ($1.81/unit) |
| Naprosyn 500mg Tablets | #30 for $76.99 | ($2.57/unit) |
| Anaprox (on 2/9/2012 at DrugStore.com) | ||
| Anaprox 275mg Tablets | #30 for $75.99 | ($2.53/unit) |
| Anaprox DS (on 2/9/2012 at DrugStore.com) | ||
| Anaprox DS 550mg Tablets | #30 for $117.99 | ($3.93/unit) |
| FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. | ||
Naproxen (C0027396) |
|
|---|---|
| Definition (CHV) | a drug that relieves pain, inflammation, and fever |
| Definition (NCI) | A drug used to treat mild pain and the symptoms of arthritis and several other conditions. It is also being studied in the treatment of bone pain in patients with cancer. Naprosyn stops the body from making substances that cause pain and inflammation. It is a type of nonsteroidal anti-inflammatory drug (NSAID) and a type of cyclooxygenase inhibitor. |
| Definition (MSH) | An anti-inflammatory agent with analgesic and antipyretic properties. Both the acid and its sodium salt are used in the treatment of rheumatoid arthritis and other rheumatic or musculoskeletal disorders, dysmenorrhea, and acute gout. |
| Definition (CSP) | 6-methoxy-alpha-methyl-2-naphthaleneacetic acid; nonsteroidal antiinflammatory drug (NSAID); acts by inhibiting cyclooxygenase and thus prostaglandin synthesis; tocolytic oxytocin antagonist. |
| Definition (NCI) | A propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Naproxen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis is responsible for the therapeutic effects of naproxen. Naproxen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. |
| Definition (PDQ) | A propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Naproxen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis is responsible for the therapeutic effects of naproxen. Naproxen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=40222&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=40222&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C680" NCI Thesaurus) |
| Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
| MSH | D009288 |
| SnomedCT | 11847009, 372588000, 363614005 |
| English | Methoxypropiocin, MNPA, Naproxen, 2-Naphthaleneacetic acid, 6-methoxy-alpha-methyl-, (S)-, d-2-(6-Methoxy-2-naphthyl)propionic Acid, 6-Methoxy-alpha-methyl-2-naphthaleneacetic Acid, naproxen, NAPROXEN, naproxen (medication), non-prescription naproxen, non-prescription naproxen (medication), Naproxen [Chemical/Ingredient], Naproxen (product), Naproxen (substance), Naproxen product (substance), Naproxen product |
| Swedish | Naproxen |
| Czech | naproxen |
| Spanish | Naproxen product (substance), Naproxen product, Naproxeno, Naproxen, naproxeno (producto), naproxeno (sustancia), naproxeno |
| Finnish | Naprokseeni |
| Russian | NAPROKSEN, НАПРОКСЕН |
| Japanese | ナプロキセン |
| Polish | Naproksen |
| French | Naproxène |
| German | Naproxen |
| Italian | Naproxene |
| Portuguese | Naproxeno |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Anaprox (C0699095) |
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|---|---|
| Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
| MSH | D009288 |
| English | anaprox, Anaprox |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Naprosyn (C0700017) |
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|---|---|
| Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
| MSH | D009288 |
| English | naprosyn, naprosin, Naprosin, Naprosyn |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Aleve (C0718343) |
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|---|---|
| Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
| MSH | D009288 |
| English | aleve, Aleve |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |