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MSM

Aka: MSM, Methylsulfonylmethane

Indications
1. Osteoarthritis
Sources
1. Endogenous: Adrenal Gland
2. Plant source: Fruits and vegetables
Efficacy: Insufficient evidence to support use
1. Only short-term (<3 months) efficacy and safety data available
2. Moderate reduction pain and swelling without an effect on joint stiffness
Dosing
1. MSM 500 mg orally three times daily (maximum: 3 grams twice daily)
References
1. Kim (2006) Osteoarthritis Cartilage 14:286-94

methylsulfonylmethane (C0058231)
Concepts	Organic Chemical (T109) , Pharmacologic Substance (T121)
MSH	C025910
SnomedCT	412192002, 412190005
English	dimethyl sulfone, Methane, sulfonylbis-, methyl sulfone, methyl sulfonmethane, methylsulfonylmethane (medication), methylsulfonylmethane, Dimethyl Sulphone, Sulfonylbismethane, MSM, Methylsulfonyl Methane, Dimethyl Sulfone, dimethyl sulfone [Chemical/Ingredient], methane methyl sulfonyl, methyl sulfones, methyl sulfonyl methane, DIMETHYL SULFONE, Dimethyl sulfone (product), Dimethyl sulfone (substance), Dimethyl sulfone, Dimethyl sulphone, MSM - Methylsulfonylmethane, Methylsulfonylmethane, METHYLSULFONYLMETHANE
Spanish	dimetilsulfona (producto), dimetilsulfona (sustancia), dimetilsulfona
Sources	Derived from the NIH UMLS (Unified Medical Language System)

Family Practice Notebook

Patients should address specific medical concerns with their physicians.

Although access to this page is not restricted, the information found here is intended for use by medical providers.

This page was written by Scott Moses, MD, last revised on 3/27/2008 and last published on 5/14/2013.

This is one of 5887 pages in the Family Practice Notebook