II. Pathophysiology

  1. Inflammatory bone changes associated with pathogenic bacteria
  2. Typically acute hematogenous spread to traumatized bone
    1. Most common in children under age 5 (50% of cases)
    2. Most commonly affects the highly vascular metaphyses of long bone

III. Symptoms

  1. Presentation within two weeks of symptom onset
  2. Fever
  3. Irritability or lethargy

IV. Signs

  1. Systemic signs of infection
  2. Local signs of infection
    1. Tenderness on palpation over involved bone
    2. Localized inflammation with erythema and swelling
    3. Decreased range of motion of adjacent joints

V. Labs

VI. Imaging

VII. Diagnosis

VIII. Management

Images: Related links to external sites (from Google)