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Labor Sedation

Aka: Labor Sedation, Latent Labor Anesthesia

Intrapartum Analgesia (Use with Sedation medications)
1. Morphine Sulfate
  1. Intravenous: 2-4 mg
  2. Intramuscular: 10-15 mg
2. Meperidine (Demerol)
  1. Dosing
    1. Intravenous: 25-50 mg
    2. Intramuscular: 50-75 mg
  2. Precautions: Not recommended
    1. No benefits in First Stage of Labor
    2. Associated with higher rate of newborn distress
    3. Sosa (2004) Am J Obstet Gynecol 191:1212-8
Sedation in latent phase: Phenothiazine
1. General
  1. Less risk of neonatal depression except high dose
2. Preparations
  1. Hydroxyzine (Vistaril)
    1. Oral: 100 mg PO qhs prn
    2. Intramuscular: 50-100 mg
    3. Intravenous: 50 mg IV
  2. Promethazine (Phenergan)
    1. Oral, Intramuscular, or rectally: 25 to 50 mg
    2. Intravenous (not FDA approved): 12.5 to 25 mg
Sedation in latent phase: Barbiturates
1. Not recommended
2. Secobarbital (Seconal) 100 mg PO or IM
  1. Risk of neonatal depression (potentiated by Opioid)
  2. No known antagonist

Family Practice Notebook

Patients should address specific medical concerns with their physicians.

Although access to this page is not restricted, the information found here is intended for use by medical providers.

This page was written by Scott Moses, MD, last revised on 10/21/2007 and last published on 5/14/2013.

This is one of 5887 pages in the Family Practice Notebook