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Recurrent Miscarriage

Aka: Recurrent Miscarriage, Recurrent Pregnancy Loss

See Also
1. First Trimester Bleeding
Indications for Recurrent Miscarriage evaluation
1. Three consecutive Miscarriages
Causes (Idiopathic in up to 60% of cases)
1. Recurrent first trimester pregnancy loss
  1. Chromosomal abnormality (5%)
  2. Antiphospholipid Antibody Syndrome (15%)
  3. Septate Uterus
  4. Polycystic Ovary Syndrome (40%)
2. Recurrent Second Trimester Pregnancy Loss
  1. Chromosomal abnormality (5%)
  2. Antiphospholipid Antibody Syndrome (15%)
  3. Bicornuate Uterus
  4. Cervical incompetence (5%)
Management
1. Preconception Counseling
  1. Folic Acid supplementation
  2. Rubella Vaccine
2. Measures to be considered
  1. Low dose Aspirin
3. Measures not found to be effective for prevention
  1. Lifestyle factors (e.g. strenuous activity)
  2. Progesterone
  3. Human chorionic gonadotropin
  4. Immunotherapy
References
1. Rutherford (2002) Practitioner 246:342-9

Recurrent pregnancy loss (C2921106)
Concepts	Pathologic Function (T046)
ICD9	646.3
ICD10	N96
English	Recurrent pregnancy loss
Sources	Derived from the NIH UMLS (Unified Medical Language System)

Family Practice Notebook

Patients should address specific medical concerns with their physicians.

Although access to this page is not restricted, the information found here is intended for use by medical providers.

This page was written by Scott Moses, MD, last revised on 9/6/2012 and last published on 5/14/2013.

This is one of 5887 pages in the Family Practice Notebook