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Ergotism
Aka: Ergotism- History
- Seen in epidemic form since the Middle Ages
- Implicated in alleged behavior of Salem witches
- Causes
- Excessive Ergot alkaloid drug intake
- Ergotamine
- Ergonovine
- Methylergometrine (Methergine)
- Methysergide (Sansert)
- Bromocriptine (Parlodel)
- Ergot alkaloid used concurrently with potentiator
- Rye or wheat infected with fungus Claviceps purpurea
- Excessive Ergot alkaloid drug intake
- Symptoms
- Signs: Gangrene of poorly vascularized distal structures
- Tip of nose
- Ears
- Fingers
- Toes