Infectious Disease Book

http://www.fpnotebook.com/

Td VaccineAka: Tetanus Diphtheria Vaccine, Tetanus Toxoid

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  1. Dose
    1. Use DTaP Vaccine for children under age 7 years
    2. Adult 0.5 ml IM
    3. Interval
      1. Low risk patients: every 8-10 years
      2. Risk of repeat exposure: every 5 years
    4. Warming vaccine in hands does not reduce pain
      1. Maiden (2003) Med J Aust 178:433
  2. Safety
    1. Safe in HIV
      1. See Immunization in HIV
    2. Safe in Pregnancy (wait until after first trimester)
      1. See Immunzation in Pregnancy
    3. Anaphylaxis rare
    4. No death has been associated with vaccine since 1978
    5. References
      1. (1996) MMWR Morb Mortal Wkly Rep 45(No. RR-12):1

Tetanus Toxoid (C0039619)

Definition (CSP)formaldehyde inactivated toxins of Clostridium tetani, used for immunization against tetanus.
Definition (NCI)A substance that is derived from the toxin released by the bacterium that causes the disease tetanus. It is used as a vaccine to prevent tetanus or to help boost the immune response to other vaccines.
Definition (PDQ)A solution of formaldehyde-deactivated toxin isolated from the bacterium Clostridium tetani. Tetanus toxoid stimulates the production of antitoxin antibodies. This agent may be used as an adjuvant in cancer vaccines. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=38508&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=38508&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2660" NCI Thesaurus)
Definition (NCI)A solution of formaldehyde-deactivated toxin isolated from the bacterium Clostridium tetani. Tetanus toxoid stimulates the production of antitoxin antibodies. This agent may be used as an adjuvant in cancer vaccines. (NCI04)
Definition (HL7V3.0)tetanus toxoid
ConceptsOrganic Chemical (T109) , Pharmacologic Substance (T121) , Immunologic Factor (T129)
MSHD013745
EnglishTetanus Toxoid, TETANUS TOXOID PREPARATION, Tetanus toxoids, TETTOX
Spanishanatoxina tetanica, toxoide tetanico
Parent ConceptsToxoids (C0040555), Vaccines administered (code = CVX)(parenteral, unless oral is noted) (C1547693), VaccineType (C1554000), Vaccine Adjuvant (C1519886), TETANUS [Ingredient] (C1376997), Drug allergen (C1320237)
SourcesCSP, HL7V2.5, HL7V3.0, MSH, MTH, NCI, NDFRT, PDQ, RXNORM, SCTSPA, SNOMEDCT, VANDF
Derived from the NIH UMLS (Unified Medical Language System)



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