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White Blood CellAka: WBC Count, Leukocyte, Leukopenia, Granulocyte

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  1. See Also
    1. Complete Blood Count
    2. Bone Marrow
  2. Physiology
    1. Granulocytes
      1. See Bone Marrow
      2. Granulocyte kinetics
        1. Cells in the Bone Marrow (90%)
          1. Proliferate and mature over 7 days
          2. Stored in the marrow up to 7 days
        2. Move to circulation with T1/2 of 6 hours (2%)
        3. Move into body tissues; die after 36 hours (8%)
    2. White Blood Cell Types
      1. Lymphocyte
      2. Monocyte
      3. Granulocytes
        1. Neutrophil
        2. Eosinophil
        3. Basophil
  3. Normal Range
    1. Age 6 Months to 2 years: 6.0 to 17.5 (Mean 11.0)
    2. Age 4 Years: 5.5 to 15.5 (Mean 9.1)
    3. Age 6 Years: 5.0 to 14.5 (Mean 8.5)
    4. Age 8 to 16 Years: 4.5 to 13.5 (Mean 8.1)
    5. Age over 21 Years: 4.5 to 11.0 (Mean 7.4)
  4. Increased White Blood Cell Count
    1. See Leukocytosis
  5. Decreased White Blood Cell Count (Leukopenia)
    1. Neutropenia (most common cause)
    2. Lymphocytopenia
    3. Monocytopenia
    4. Eosinopenia

granulocyte (C0018183)

Definition (MSH)Leukocytes with abundant granules in the cytoplasm. They are divided into three groups according to the staining properties of the granules: neutrophilic, eosinophilic, and basophilic. Mature granulocytes are the NEUTROPHILS; EOSINOPHILS; and BASOPHILS.
Definition (CSP)leukocytes with abundant neutrophilic, eosinophilic or basophilic granules in the cytoplasm; mature granulocytes are the neutrophils, eosinophils, and basophils.
Definition (NCI)A leucocyte with conspicuous cytoplasmic granules. In humans the granulocytes are also classified as polymorphonuclear leucocytes and are subdivided according to the staining properties of the granules into eosinophils, basophils and neutrophils.
ConceptsCell (T025)
MSHD006098
Englishgranular leukocyte, granulocyte, Granulocytes, Granulocytic, Granulocytic cell
Spanishcelula granulocitica, granulocito
Parent ConceptsLeukocytes (C0023516), Bone Marrow Cells (C0005955), Myeloid Cells (C0887899), granulocyte (C0018183), Entire cell (C1269647)
SourcesAOD, CSP, LCH, LNC, MSH, MTH, NCI, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)


Leukopenia (C0023530)

Definition (CSP)reduction in the number of leukocytes in the blood, the count being 5000 per cubic millimeter or less.
Definition (NCI)(LOO-ko-PEE-nya) A condition in which the number of leukocytes (white blood cells) in the blood is reduced.
ConceptsDisease or Syndrome (T047)
ICD9288.50, 288.50
MSHD007970
EnglishDecreased blood leucocyte number, Decreased blood leukocyte number, LEUCOPENIA, Leukocytopenia, Leukocytopenias, Leukopenia, Leukopenias
Spanishdisminucion del numero de leucocitos, leucopenia
Parent ConceptsLeukocyte Disorders (C0023510), Decreased white blood cell count (C0750394), Cytopenia (C0010828), White blood cell count laboratory result (C0427512), Duplicate concept (C1274013)
SourcesAOD, COSTAR, CSP, CST, ICD9CM, MSH, MTH, MTHICD9, NCI, NDFRT, OMIM, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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