Hematology and Oncology Book

Bone Marrow Disorders

Lymphatic Disorders

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Thrombin Time

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  1. Normal
    1. Range: 11.3-18.5 seconds
  2. Increased
    1. Thrombolytic therapy
    2. Heparin therapy
    3. Disseminated Intravascular Coagulation (DIC)
    4. Hypofibrinogenemia
    5. Dysfibrinogenemia

Thrombin Time Assay (C0677634)

Definition (MSH)Clotting time of PLASMA mixed with a THROMBIN solution. It is a measure of the conversion of FIBRINOGEN to FIBRIN, which is prolonged by AFIBRINOGENEMIA, abnormal fibrinogen, or the presence of inhibitory substances, e.g., fibrin-fibrinogen degradation products, or HEPARIN. BATROXOBIN, a thrombin-like enzyme unaffected by the presence of heparin, may be used in place of thrombin.
ConceptsLaboratory Procedure (T059)
MSHD013918
EnglishFibrin time, Reptilase clotting time, Reptilase Time, Reptilase Times, Thrombin Time, Thrombin time - observation, Thrombin Time Assay, Thrombin Times, TT - Thrombin time
Spanishtiempo de coagulacion con reptilasa, tiempo de fibrina, tiempo de reptilasa, tiempo de trombina
Parent ConceptsBlood coagulation tests (C0005790), Blood Physiologic Phenomena (C1257981), Extrinsic coagulation pathway screening (C0430232), Fibrinogen screening (C1327647), Duplicate concept (C1274013)
SourcesAOD, MSH, MTH, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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