Hematology and Oncology Book

Bone Marrow Disorders

Lymphatic Disorders

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Haptoglobin

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  1. Normal
    1. Range: 50-220 mg/dl
    2. Acute phase reactant
  2. Increased
    1. Inflammation
    2. Collagen-Vascular Disease
    3. Infection
    4. Androgens
  3. Decreased
    1. Hemolysis (intravascular)
    2. Megaloblastic Anemia
    3. Severe liver disease
    4. Large hematomas
    5. Epstein Bar Virus (EBV)
    6. Cytomegalovirus
    7. Oral Contraceptives

Haptoglobins (C0018595)

Definition (MSH)Plasma glycoproteins that form a stable complex with hemoglobin to aid the recycling of heme iron. They are encoded in man by a gene on the short arm of chromosome 16.
Definition (CSP)a blood glycoprotein found in the alpha globulin fraction which binds free hemoglobin.
ConceptsAmino Acid, Peptide, or Protein (T116) , Biologically Active Substance (T123)
MSHD006242
EnglishHaptoglobin, Haptoglobins, Hp - Haptoglobin
Spanishhaptoglobina
Parent ConceptsMucoproteins (C0026714), Alpha-Globulins (C0002211), Globin (C0017645), Binding Protein (C0242210), Acute-Phase Proteins (C0001347), Hemoglobin breakdown product (C0475356)
SourcesAOD, CSP, LCH, LNC, MSH, MTH, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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