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Fibrin Degradation ProductsAka: FDP
- Normal
- Range: <10 ug/ml
- Increased
- Disseminated Intravascular Coagulation (DIC)
- Primary Fibrinolysis
- Pulmonary Embolus
- Severe liver disease
- False positive
- Rheumatoid Factor (RF) present
Fibrin split products (C0163275) | |
|---|---|
| Definition (MSH) | Soluble protein fragments formed by the proteolytic action of plasmin on fibrin or fibrinogen. FDP and their complexes profoundly impair the hemostatic process and are a major cause of hemorrhage in intravascular coagulation and fibrinolysis. |
| Definition (SPN) | A fibrinogen/fibrin degradation products assay is a device used to detect and measure fibrinogen degradation products and fibrin degradation products (protein fragments produced by the enzymatic action of plasmin on fibrinogen and fibrin) as an aid in detecting the presence and degree of intravascular coagulation and fibrinolysis (the dissolution of the fibrin in a blood clot) and in monitoring therapy for disseminated intravascular coagulation (nonlocalized clotting in the blood vessels). |
| Concepts | Amino Acid, Peptide, or Protein (T116) , Biologically Active Substance (T123) |
| MSH | D005338 |
| English | Antithrombin VI, FDP, FDP - Fibrinogen degradation agent, FDP - Fibrinogen degradation product, FFDP, Fibrin degradation agent, Fibrin degradation product, Fibrin Degradation Products, Fibrin Fibrinogen Degradation Products, Fibrin Fibrinogen Split Products, Fibrin split agents, Fibrin split products, Fibrinogen degrad. products, Fibrinogen degradation agent, Fibrinogen degradation product, Fibrinogen split agents, Fibrinogen split products, FSP |
| Spanish | producto de degradacion de fibrina, producto de degradacion de fibrinogeno |
| Parent Concepts | Fibrin (C0015982), Fibrinogen (C0016006), Fibrinolytic system factor (C0443796), Fibrin AND/OR fibrinogen product (C1268931), Duplicate concept (C1274013) |
| Sources | LNC, MSH, MTH, SCTSPA, SNOMEDCT, SPN Derived from the NIH UMLS (Unified Medical Language System) |
