See Also
1. Cardiac Risk Factor
2. C-Reactive Protein
Indications
1. Not recommended for routine screening currently
  1. Not specific for Coronary Artery Disease
  2. Large day to day variablity in values
  3. No clear strategy for elevated values
  4. Kushner (2002) Arch Intern Med 162:867
  5. Ridker (2002) N Engl J Med 347:1557
2. High-Sensitivity CRP may be used in high-risk patient
  1. hs-CRP >3 mg/L predicts more ischemic episodes
  2. Elevated hs-CRP may dictate more intense therapy
  3. Rosenson (2003) Am J Cardiol 92:10i
Efficacy: Increased C-RP as Cardiac Risk marker
1. Comparatively weak predictor of heart disease
2. Odds ratio C-RP: 1.45
3. Odds ratio Increased SBP: 1.50
4. Odds ratio Tobacco Abuse: 1.87
5. Odds ratio Increased Total Cholesterol: 2.35
6. Danesh (2004) N Engl J Med 350:1387

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This page was written by Scott Moses, MD. This page was last revised before 5/10/08, prior to consistent tracking of revision date. This page was last published on 2/26/2010. Please send comments and questions to the editor. Contact information may be found on the page About the Family Practice Notebook. These pages are best viewed with Microsoft Internet Explorer 6.0.