II. Associated Conditions: Renal dysfunction
- HIV Nephropathy (AIDS associated Nephropathy)
- Fluid and Electrolyte abnormalities
- SIADH and Hyponatremia common due to occult infection
- Drug induced Renal toxicity
- See Nephrotoxic Drug
- Amphotericin B
- Foscarnet
- Pentamidine
- Bactrim
- NSAIDs
- Tenofovir disoproxil Fumarate (TDF)
- Causes proximal tubule dysfunction (e.g. Hypophosphatemia) and decreased Renal Function
- Avoid if GFR <60 ml/min and discontinue if GFR falls more than 25% or <60 ml/min
- May safely use Tenofovir Alafenamide as alternative (less nephrotoxic)