See Also
1. Anti-Retroviral Therapy
Class
1. Anti-retroviral agent
2. Entry Inhibitor
Mechanism
1. Blocks HIV to chemokine (CCR5 - R5) receptor binding on CD4 cells
2. Since only effective on R5 cells - requires R5 tropism test prior to initiating Maraviroc
Indications
1. Anti-retroviral naive patients
2. Anti-retroviral experienced patients
Adverse Effects
1. Well tolerated overall
2. Fever
3. Upper respiratory symptoms (e.g. cough, Bronchitis)
4. Abdominal Pain
5. Rash
6. Orthostatic Hypotension
7. Myalgia
8. Hepatotoxicity (may be associated with rash and Eosinophilia)
9. Increased Myocardial Infarction risk
Monitoring
1. Requires R5 tropism test prior to initiating Maraviroc
References
1. (2009) Treat Guidel Med Lett 7(78): 11-22
2. Reust (2011) Am Fam Physician 83(12): 1443-51

Medication Costs
Selzentry (on 2/9/2012 at DrugStore.com)
Selzentry 150mg Tablets	#30 for $530.00	($17.67/unit)
Selzentry 300mg Tablets	#30 for $570.99	($19.03/unit)
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information.

Family Practice Notebook

Patients should address specific medical concerns with their physicians.

Although access to this page is not restricted, the information found here is intended for use by medical providers.

This page was written by Scott Moses, MD, last revised on 10/8/2011 and last published on 5/14/2013.

This is one of 5887 pages in the Family Practice Notebook