Human Immunodeficiency Virus Book

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HIV Test

Aka: HIV Test, HIV Antibody, HIV Screening, HIV Labs
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  1. Indications
    1. See HIV Screening Indications
  2. Labs: HIV Detection
    1. Tests
      1. Rapid HIV Tests (office based)
        1. Test Sensitivity and Test Specificity approach 100%
        2. OraQuick Rapid Antibody Test
        3. Uni-Gold Recombigen
      2. Home tests
        1. OraQuick In-Home HIV Test (oral swab based)
          1. Test Sensitivity: 92% (false negative rate: 1 in 12)
          2. Test Specificity: 99.98% (false positive rate: 1 in 5000)
          3. Most accurate at 3 months after exposure
      3. Traditional HIV Screening Tests
        1. HIV Enzyme Immunoassay ($20)
      4. HIV Confirmatory Tests
        1. HIV Western Blot Assay
    2. False-negative test causes (Consider PVL Test)
      1. Acute seroconversion (<4 weeks of HIV Infection)
      2. Advanced AIDS
      3. Autoimmune condition
      4. Hemodialysis patients (Renal Failure)
      5. Multiple pregnancies
      6. Multiple transfusions
      7. Cystic Fibrosis
      8. Liver disease
      9. Intravenous Drug Abuse
      10. Immunization
        1. HIV vaccination (experimental only)
        2. Recent other Immunization
  3. Labs: HIV Activity
    1. Primary Tests
      1. HIV Viral activity
      2. CD4 Cell Count
    2. Other Tests
      1. Viral culture
      2. Direct detection of p24 antigen
        1. Positive at 14-15 days from infection (falls within 6-8 weeks)
        2. Consider for Acute Retroviral Syndrome diagnosis
        3. Test Sensitivity: 88.7%
        4. Test Specificity: 100%
  4. Labs: Related Sexually Transmitted Disease Testing
    1. Syphilis Serology (Rapid Plasma Reagin, VDRL)
    2. Hepatitis B Serology
    3. Hepatitis C Serology
    4. Gonorrhea Culture
    5. Chlamydia Antigen
  5. Labs: Disease Screening Related to Advanced HIV or AIDS
    1. Tuberculin Skin Test (PPD, Mantoux)
      1. Dose: 0.5 cc injected (contrast with standard 0.1 cc)
      2. Positive: >5 mm (contrast with standard 10 mm)
    2. Cytomegalovirus Serology (CMV)
    3. Toxoplasmosis Titer
    4. Gynecologic examination with Pap Smear
      1. HIV associated with advanced Cervical Cancer
  6. References
    1. Mylonakis (2000) Arch Intern Med 160:2386-8
    2. (1997) Med Lett Drugs Ther 39:81-3

HIV screen (C0459958)

Concepts Laboratory Procedure (T059)
SnomedCT 171121004, 395052001, 393926007, 148344008, 392970006
English HIV screen, HIV screening (procedure), Human immunodeficiency virus (HIV) screening (procedure), Human immunodeficiency virus (HIV) screening, HIV screening test (procedure), AIDS HIV tests, HIV screening tests, HIV testing, HIV tests, AIDS hiv testing, AIDS testing, AIDS tests, HIV test, AIDS test, screening HIV, AIDS (HTLV-III) screening, HIV screening, HIV screening test
Spanish cribado de VIH, detección selectiva de VIH, detección selectiva de virus de inmunodeficiencia humana, detección selectiva de VIH (procedimiento), HIV screening test, cribado para la detección del HIV, cribado para la detección del virus de la inmunodeficiencia humana, HIV screening, detección selectiva de virus de inmunodeficiencia humana (procedimiento), cribado para la detección del virus de la inmunodeficiencia humana (procedimiento), detección selectiva de HIV, pesquisa de HIV, pesquisa de VIH, screening de HIV, screening de VIH, tamizaje de HIV, tamizaje de VIH
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Human immunodeficiency virus test (C1321876)

Definition (CSP) any clinical test whose results can be used to diagnosis AIDS; including tests for HIV infection, CD4 lymphocyte count, tests for microorganisms such as Pneumocystis, etc.; for diagnosis by symptoms and other factors, use AIDS DIAGNOSIS.
Concepts Laboratory Procedure (T059)
SnomedCT 143221005, 165813002
English HIV ANTIBODY TEST, AIDS test, HIV Antibody Test (HTLV III Antibody Test), AIDS antibody test, Acqu immunodefic syndr ab test, HIV - Hum immunodef virus test, Human immunodefic virus test, HIV antibody, HIV test, HIV tests, HIV TEST, HIV Measurement, Test;HIV, AIDS/HIV test, AIDS - Acquired immunodeficiency syndrome antibody test, Acquired immunodeficiency syndrome antibody test, HIV - Human immunodeficiency virus test, Human immunodeficiency virus test (procedure), Human immunodeficiency virus test, AIDS Testing, HIV Testing, Test;AIDS(HIV)
Italian Anticorpo anti-virus dell'immunodeficienza umana, Test del virus dell'immunodeficienza umana
Dutch HIV-tests, HIV-antistof, HIV-test
French Tests VIH, Sérologie VIH, Anticorps anti-HIV
German HIV-Tests, HIV-Antikoerper, HIV-Test
Portuguese Testes de HIV, Anticorpos anti-VIH, Teste de HIV
Spanish Pruebas del VIH, Human immunodeficiency virus test, prueba de detección del virus de HIV, prueba de detección del virus de VIH, prueba de detección del virus de inmunodeficiencia humana (procedimiento), prueba de detección del virus de inmunodeficiencia humana, Anticuerpos anti-VIH, Prueba VIH
Japanese ＨＩＶ検査, ＨＩＶ抗体, HIVｹﾝｻ, HIVｺｳﾀｲ
Czech Vyšetření na HIV, Protilátky proti viru HIV
Hungarian HIV antitest, HIV vizsgálatok, HIV vizsgálat
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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