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Serum Gastrin
Aka: Serum Gastrin, Gastrin
- Normal: <180 pg/ml
- Increased: Most important causes
- Medications (most common cause)
- Proton Pump Inhibitors (e.g. Omeprazole)
- Associated with 2-5 fold increase in Gastrin level
- H2 Blockers
- Pernicious Anemia
- Very low Stomach acid level (contrast with Zollinger-Ellison)
- Zollinger-Ellison Syndrome or Gastrinoma (rare)
- Very high Gastrin level
- Gastrin Level remains increased despite withdrawal of Proton Pump Inhibitors and other possible causes
- High Stomach acid level
- Measured with nasogastric suction over one hour
- Contrast with very low Stomach acid level in Pernicious Anemia
- Increased: Other Causes
- Hyperparathyroidism
- Retained gastric antrum
- Chronic atrophic Gastritis
- Pyloric obstruction
- Gastric neoplasm
- Chronic Renal Failure