Gastroenterology Book

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Liver Function TestAka: LFT

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  1. See Also
    1. Liver Function Test Abnormality
  2. Labs: Markers of liver function and protein synthesis
    1. Serum Albumin
    2. Serum Bilirubin
    3. Prothrombin Time
  3. Labs: Markers of hepatocellular disease
    1. Alanine Aminotransferase (ALT)
      1. Most specific for hepatocyte injury
    2. Aspartate Aminotransferase (AST)
      1. Less specific than ALT (present outside liver)
    3. AST to ALT ratio
      1. Most liver conditions (e.g. NASH): Ratio <1
      2. Alcoholism: Ratio >2
      3. Wilson's Disease >4
    4. Lactate Dehydrogenase (LDH)
      1. Least specific for hepatocyte injury
      2. Dramatically increased in ischemic hepatitis
      3. Increased with alk phos in liver metastases
  4. Labs: Markers of cholestasis
    1. Alkaline Phosphatase
    2. Gamma glutamyl transferase (GGT)
    3. Serum Bilirubin
  5. Labs: Disease specific markers
    1. Definite value
      1. Viral Hepatitis Serology
      2. Iron studies
      3. Ceruloplasmin (Wilson's Disease)
    2. Limited value: Anti-Smooth muscle Ab
      1. Antimitochondrial Antibody
      2. Alpha-1 antitrypsin

Liver Function Tests (C0023901)

ConceptsLaboratory Procedure (T059)
MSHD008111
EnglishHepatic function panel, LFT - Liver function test, LFT's, Liver funct. test -gen., Liver function test, Liver Function Tests, Liver function tests - general
FrenchTests de fonction hepatique
ItalianTests epatici
Spanishgrupo de pruebas de la funcion hepatica, perfil de funcion hepatica, pruebas de funcion hepatica - general
Parent Conceptsdigestive system diagnosis (C0679566), Diagnostic Techniques, Digestive System (C0011907), Liver Function Tests (C0023901), Organ or system related test (C0200380), Biochemical test (C0430027), Ambiguous concept (C1274012), Duplicate concept (C1274013)
SourcesAOD, LCH, MSH, MTH, MTHMST, MTHMSTFRE, MTHMSTITA, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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