Gastroenterology Book

http://www.fpnotebook.com/

Rotavirus

Aka: Rotavirus
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  1. See Also
    1. Diarrhea
    2. Infectious Diarrhea
  2. Epidemiology
    1. Most common cause of acute Infectious Diarrhea in the United States
    2. Accounts for 35% of child hospitalizations for Diarrhea
    3. Peak ages affected: 6 months to 2 years old
      1. Uncommon under age 6 months or over age 4 years
    4. Infection peaks in March (mid-January to late May)
    5. Incidence: 54,000 cases per year in United States
    6. Mortality: 100 deaths per year in United States
  3. Pathophysiology
    1. Antibody to Rotavirus is protective
    2. Self limited Infection
    3. Transmission: Fecal-oral route
    4. Incubation: 1-3 days
  4. Symptoms
    1. Emesis for 3 days
    2. Severe Watery Diarrhea for 3-8 days
    3. Fever
    4. Upper respiratory symptoms
  5. Prevention
    1. Careful hand washing
    2. See Rotavirus Vaccine
      1. Limited use due to Intussusception risk
  6. References
    1. Staat (2002) Pediatr Infect Dis J 21:221-7

Rotavirus (C0035870)

Definition (NCI) A genus of double stranded RNA viruses that carry 11 unique double helix molecules of RNA that encode one or two proteins each. The RNA is surrounded by a three-layered icosahedral protein capsid. Viral particles are up to 76.5 nm in diameter and are not enveloped.
Definition (MSH) A genus of REOVIRIDAE, causing acute gastroenteritis in BIRDS and MAMMALS, including humans. Transmission is horizontal and by environmental contamination. Seven species (Rotaviruses A thru G) are recognized.
Definition (CSP) 6 serogroups described; group A occurs in mammals and birds; group B in humans, pigs, cattle, sheep and rats; group C in pigs and rarely humans; groups D and F in poultry; and group E in pigs.
Concepts Virus (T005)
MSH D012401
SnomedCT 70614005, 417542000
English Rotaviruses, rotavirus, ROTAVIRUS, Rotavirus, NOS, Genus: Rotavirus, Rotaviral, 321 ROTAVIRUS, rotaviruses, Rotavirus (organism), Rotavirus, Genus Rotavirus (organism), Genus Rotavirus
Swedish Rotavirus
Spanish rotavirus (organismo), género: Rotavirus, rotavirus, Rotavirus, Rotavirus, SAI, género Rotavirus (organismo), género Rotavirus
Czech Rotavirus
Finnish Rotavirus
Russian NEONATAL'NOI DIAREI TELIAT VIRUS, ROTAVIRUS, НЕОНАТАЛЬНОЙ ДИАРЕИ ТЕЛЯТ ВИРУС, РОТАВИРУС
Croatian ROTAVIRUS
Polish Rotavirus
French Rotavirus
German Rotavirus
Italian Rotavirus
Dutch Rotavirus, Virus, Rota-
Portuguese Rotavirus
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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