Gastroenterology Book

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Hepatomegaly

Aka: Hepatomegaly, Liver Enlargement
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  1. See Also
    1. Hepatomegaly in Newborns
    2. Splenomegaly
  2. Causes: Hepatomegaly
    1. Liver displacement (Palpable liver, no Hepatomegaly)
      1. Obstructive lung disease (Asthma, COPD)
      2. Adjacent mass (Cholecystitis, abscess)
      3. Thin patient
    2. Infectious
      1. AIDS
      2. Hepatic Abscess (e.g. Amebiasis)
      3. Relapsing Fever
      4. Echinococcal cysts
      5. Schistosomiasis
      6. Kala Azar
    3. Hepatitis
      1. Alcoholic Hepatitis
      2. Autoimmune Hepatitis
      3. Viral Hepatitis
    4. Congestive Hepatomegaly (often precedes edema)
      1. Congestive Heart Failure (systemic venous congestion)
      2. Constrictive Pericarditis
      3. Tricuspid stenosis
    5. Miscellaneous
      1. Wilson's Disease
      2. Fatty Liver
      3. Cirrhosis
      4. Hemochromatosis
      5. Primary Sclerosing Cholangitis
      6. Cholestasis
      7. Mixed cryoglobulinemia
      8. Congenital hepatic fibrosis
      9. Polycystic liver disease
      10. Hurler's Syndrome
      11. Gaucher's Disease
      12. Sarcoidosis
      13. Amyloidosis
    6. Malignancy
      1. Intraabdominal malignancy
      2. Pancreatic Cancer
      3. Hepatocellular Carcinoma
    7. Medication toxicity
      1. See Hepatotoxins
      2. NRTI (e.g. Stavudine)
  3. Causes: Hepatosplenomegaly
    1. See Splenomegaly
    2. Babesiosis
    3. Chaga's Disease
    4. Mononucleosis
    5. Malaria
    6. Beta Thalassemia major
    7. Essential-mixed cryoglobulinemia
    8. Viral Arthritis (e.g. Parvovirus)
    9. Severe congestive Hepatomegaly (see Hepatomegaly)
    10. Acute Lymphoblastic Leukemia
    11. Mast cell disorders (mastocytosis)
  4. Evaluation
    1. Step 1: Confirm Liver Enlargement versus displacement
    2. Step 2: Check Serum AST and Serum ALT
      1. If positive then go to step 3
      2. If negative then go to step 4
    3. Step 3: Check for Viral Hepatitis
    4. Step 4: Check Abdominal CT for liver lesion
    5. Step 5: Consider congestive Hepatomegaly (e.g. CHF)
    6. Step 6: Consider liver biopsy

Hepatomegaly (C0019209)

Definition (NCI) Enlarged liver.
Definition (MSH) Enlargement of the liver.
Definition (NCI) Abnormal enlargement of the liver.
Concepts Sign or Symptom (T184)
MSH D006529
ICD9 789.1
ICD10 R16.0
SnomedCT 207231001, 207233003, 207232008, 158514002, 158515001, 158513008, 80515008
English Hepatomegaly, HEPATOMEGALY, LARGE LIVER, LIVER ENLARGEMENT, Hepatomegaly NOS, Liver enlargement, [D]Hepatomegaly (context-dependent category), [D]Hepatomegaly NOS (context-dependent category), [D]Liver enlargement (context-dependent category), [D]Hepatomegaly, [D]Hepatomegaly NOS, [D]Liver enlargement, liver enlargement, hepatic enlargement, enlarged liver, hepatomegaly (physical finding), hepatomegaly, [D]Liver enlargement (situation), [D]Hepatomegaly NOS (situation), [D]Hepatomegaly (situation), Enlarged Liver, Liver, Enlarged, Hepatomegaly [Disease/Finding], enlargement of liver, Enlarged;liver, large liver, enlarged livers, Large liver, Large liver (disorder), enlargement; liver, liver; enlargement, Enlargement of liver
French HEPATOMEGALIE, AUGMENTATION DU VOLUME DU FOIE, Hepatomegalie, Hépatomégalie, Hypertrophie du foie, Hypertrophie hépatique
Portuguese HEPATOMEGALIA, Aumento de volume do fígado, AUMENTO DE VOLUME DO FIGADO, Hepatomegalia, Fígado Aumentado, Fígado Hipertrófico
Spanish HEPATOMEGALIA, hígado grande, Aumento de tamaño del hígado, [D]hepatomegalia, SAI (categoría dependiente del contexto), [D]agrandamiento del hígado (categoría dependiente del contexto), [D]hepatomegalia (categoría dependiente del contexto), [D]Hepatomegaly, [D]Liver enlargement, [D]Hepatomegaly NOS, HIGADO AUMENTADO DE TAMANO, [D]hepatomegalia, SAI (situación), [D]hepatomegalia, SAI, [D]agrandamiento del hígado (situación), [D]hepatomegalia (situación), [D]agrandamiento del hígado, [D]hepatomegalia, hepatomegalia (trastorno), hepatomegalia, Hepatomegalia, Hígado Agrandado, Higado Agrandado
German HEPATOMEGALIE, Lebervergroesserung, LEBERVERGROESSERUNG, Hepatomegalie, Lebervergrößerung
Dutch leververgroting, lever; vergroting, vergroting; lever, hepatomegalie, Hepatomegalie, Vergrote lever
Swedish Leverförstoring, FORSTORAD LEVER
Japanese ｶﾝｼｭﾀﾞｲ, 肝腫, 肝腫脹, 肝腫大, 肝臓腫大
Czech hepatomegalie, Hepatomegalie, Zvětšení jater
Finnish Hepatomegalia, SUURENTUNUT MAKSA
Italian Fegato ingrossato, Epatomegalia
Russian GEPATOMEGALIIA, ГЕПАТОМЕГАЛИЯ
Norwegian FORSTORRET LEVER/HEPATOMEGALI - r16.0 - r16.2
Danish Hepatomegali
Hungarian hepatomegalia, Májmegnagyobbodás, Hepatomegalia
Basque HEPATOMEGALIA
Polish Hepatomegalia, Powiększenie wątroby
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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