Ophthalmology Book

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Cornea

Aka: Cornea, Corneal Epithelium, Bowman's Membrane, Corneal Stroma, Corneal Endothelium, Descemet's Membrane
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  1. See Also
    1. Refractive Error
    2. Corneal Abrasion
    3. Fluorescein
  2. Definition
    1. Transparent front refractive window of eye
  3. Anatomy
    1. eyeGlobeXsGrayBB869.gifLewis (1918) Gray's Anatomy 20th ed (in public domain at Yahoo or BartleBy)
    2. eyeCorneaLensGrayBB883.gifLewis (1918) Gray's Anatomy 20th ed (in public domain at Yahoo or BartleBy)
  4. Physiology
    1. Dimensions
      1. Vertical: 11.6 mm
      2. Horizontal: 11.5 mm
      3. Thickness
        1. Peripheral: 1 mm
        2. Central: 0.55 mm
    2. Five distinct layers
      1. Epithelium (Exterior layer of Cornea)
        1. Prevents infection
        2. Smooth refractive surface
      2. Bowman's Membrane
      3. Stroma (90% of Corneal thickness)
        1. Composed of collagen fibrils intertwined
        2. Supportive structure of Cornea
      4. Endothelium
        1. Dehydrates Cornea via Na-K ATP Pump
        2. Relative dehydration maintains Corneal clarity
      5. Descemet's Membrane (Interior Layer of Cornea)
        1. Endothelium basement membrane
    3. Function
      1. Barrier protection
      2. UV light filtration
      3. Refraction
        1. Cornea provides 65-75% of eye's focusing power
        2. Unlike lens, Cornea's Refraction power is fixed
    4. Blood supply
      1. No direct blood supply to maintain transparency
      2. All nutrition supplied indirectly
        1. Tears
        2. Ambient oxygen
        3. Aqueous Humor of anterior chamber

Corneal Diseases (C0010034)

Definition (MEDLINEPLUS)

Your cornea is the outermost layer of your eye. It is clear and shaped like a dome. The cornea helps to shield the rest of the eye from germs, dust, and other harmful matter. It also helps your eye to focus. If you wear contact lenses, they float on top of your corneas.

Problems with the cornea include

  • Refractive errors
  • Allergies
  • Infections
  • Injuries
  • Dystrophies—conditions in which parts of the cornea lose clarity due to a buildup of cloudy material

Treatments of corneal disorders include medicines, corneal transplantation and corneal laser surgery.

NIH National Eye Institute

Definition (MSH) Diseases of the cornea.
Definition (CSP) pathological process affecting the transparent anterior portion of the fibrous coat of the eye.
Concepts Disease or Syndrome (T047)
MSH D003316
ICD9 371.9
ICD10 H18.9
SnomedCT 15250008, 193856004, 155160005, 267733008, 193794007
English Corneal Diseases, Disease, Corneal, Diseases, Corneal, DISEASE OF CORNEA, cornea disorder, DISEASES OF THE CORNEA, DISEASES OF THE CORNEA AND CONJUNCTIVA, Disease of cornea, NOS, Corneal disorder NOS, DISORDER CORNEAL, Disorder of cornea, NOS, Disorder of cornea, unspecified, CORNEAL DISORDER (NOS), CORNEAL DISORDERS, CORNEAL DIS, Disease of cornea, cornea, corneal disorder, cornea (diagnosis), A-75 DISEASES OF THE CORNEA AND CONJUNCTIVA, A-750-754 DISEASES OF THE CORNEA, Corneal disorder (NOS), Disorder corneal, Corneal disorder NOS (disorder), Unspecified disorder of cornea, Corneal Diseases [Disease/Finding], cornea disease, disease cornea, diseases corneal, cornea diseases, diseases of the cornea, cornea disorders, corneal disease, corneal diseases, corneal disorders, Corneal Disorders, Corneal disorder, cornea; disorder, disease (or disorder); cornea, Corneal disorders NOS, Corneal disorders, Disease of cornea (disorder), Disorder of cornea, Disorder of cornea (disorder), Corneal Disease, Corneal Disorder, Unspecified corneal disorder
Italian Patologia della cornea, Patologia corneale, Alterazioni corneali non specificate, Patologia della cornea (NAS), Patologia della cornea non specificata, Malattie della cornea
Dutch aandoening cornea, niet-gespecificeerde cornea-aandoening, cornea-aandoening (NAO), cornea-aandoening NAO, aandoening; cornea, cornea; aandoening, Aandoening van cornea, niet gespecificeerd, cornea-aandoening, Corneaziekte, Corneaziekten, Ziekte, cornea-, Ziekten, cornea-
French Trouble cornéen SAI, Affection de la cornée, Trouble cornéen non précisé, Affection cornéenne SAI, Trouble cornéen, Kératopathies, Maladies cornéennes, Maladies de la cornée
German Erkrankung der Hornhaut, Hornhauterkrankung NNB, unspezifische Hornhauterkrankung, Hornhauterkrankung (NNB), Affektion der Hornhaut, nicht naeher bezeichnet, Erkrankung der Kornea, Korneakrankheiten, Hornhautkrankheiten (Auge)
Portuguese Afecção da córnea, Afecção da córnea NE, Alteração da córnea NE, Afecção NE da córnea, Alteração da córnea, Doenças da Córnea
Spanish Trastorno corneal, Trastorno corneano no especificado, Trastorno de la córnea (NEOM), enfermedad de la córnea (trastorno), Corneal disorders, Corneal disorder NOS, Corneal disorders NOS, trastorno corneal NEOM, trastorno corneal, SAI (trastorno), trastorno corneal, SAI, trastorno corneal, Alteración corneal, trastorno de la córnea, trastorno de la córnea (trastorno), enfermedad de la córnea, Enfermedades de la Córnea, Enfermedades de la Cornea
Japanese 角膜障害NOS, 角膜障害, 角膜障害(NOS), カクマクショウガイ, カクマクショウガイNOS
Swedish Hornhinnesjukdomar
Czech rohovka - nemoci, Nespecifikované onemocnění rohovky, Onemocnění rohovky NOS, Onemocnění rohovky (NOS), Onemocnění rohovky
Finnish Sarveiskalvon sairaudet
Russian ROGOVITSY BOLEZNI, РОГОВИЦЫ БОЛЕЗНИ
Korean 상세불명의 각막의 장애
Croatian ROŽNICA, BOLESTI
Polish Choroby rogówki
Hungarian Nem meghatározott cornea betegség, Cornea betegség (K.m.n.), Szaruhártya-betegség, Cornea betegség k.m.n., Szaruhártya betegség
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Corneal Stroma (C0010040)

Definition (MSH) The lamellated connective tissue constituting the thickest layer of the cornea between the Bowman and Descemet membranes.
Definition (CSP) lamellated connective tissue constituting the thickest layer of the cornea between the Bowman and Descemet membranes.
Definition (NCI) The lamellated connective tissue constituting the thickest layer of the cornea between the Bowman and Descemet membranes. (MeSH)
Concepts Body Part, Organ, or Organ Component (T023)
MSH D003319
SnomedCT 50546002
English Corneal Stromas, Stroma, Corneal, Stromas, Corneal, Cornea, substantia propria, Substantia propria of cornea, NOS, corneal stroma, Substantia propria corneae, Stroma of cornea, Substantia propria of cornea, Structure of substantia propria of cornea (body structure), Structure of substantia propria of cornea, Corneal Stroma
Spanish Estroma de la Cornea, Estroma de la Córnea, Sustancia Propia, Estroma Corneal, estroma de la córnea, estructura de la sustancia propia de la córnea (estructura corporal), estructura de la sustancia propia de la córnea, sustancia propia de la córnea
French Stroma de la cornée, Stroma cornéen
Swedish Korneal stroma
Czech rohovka - stroma
Portuguese Substância Própria, Estroma Corneano, Estroma da Córnea
Finnish Sarveiskalvon strooma
Russian ROGOVITSY STROMA, РОГОВИЦЫ СТРОМА
Latvian Radzenes stroma
Polish Zrąb rogówki
German Stroma corneae
Italian Stroma della cornea
Dutch Substantia propria corneae
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Corneal Endothelium (C0014259)

Definition (MSH) Single layer of large flattened cells covering the surface of the cornea.
Definition (CSP) single layer of large flattened cells covering the surface of the cornea.
Concepts Tissue (T024)
MSH D004728
SnomedCT 65431007
English Endothelium, Corneal, corneal endothelium, Corneal endothelium, Structure of corneal endothelium (body structure), Structure of corneal endothelium, Corneal Endothelium
French Endothélium de la cornée, Endothélium cornéen
Swedish Hornhinneendotel
Czech endotel rohovkový
Portuguese Epitélio Posterior, Endotélio Corneano, Endotélio da Córnea, Epitélio Posterior Corneano, Epitélio Posterior da Córnea
Spanish Epitelio Posterior, Endotelio de la Córnea, Endotelio Corneal, Endotelio de la Cornea, Epitelio Posterior de la Cornea, Epitelio Corneal Posterior, endotelio de la córnea, estructura del endotelio de la córnea (estructura corporal), estructura del endotelio de la córnea
Finnish Sarveiskalvon endoteeli
Russian ROGOVICHNYI ENDOTELII, ENDOTELII PERVICHNOI KAMERY GLAZA, GLAZA PEREDNEI KAMERY ENDOTELII, ENDOTELII ROGOVICHNYI, PEREDNEI KAMERY GLAZA ENDOTELII, ГЛАЗА ПЕРЕДНЕЙ КАМЕРЫ ЭНДОТЕЛИЙ, ПЕРЕДНЕЙ КАМЕРЫ ГЛАЗА ЭНДОТЕЛИЙ, РОГОВИЧНЫЙ ЭНДОТЕЛИЙ, ЭНДОТЕЛИЙ ПЕРВИЧНОЙ КАМЕРЫ ГЛАЗА, ЭНДОТЕЛИЙ РОГОВИЧНЫЙ
Japanese 角膜内皮, 前房内皮, 内皮-前眼房, 前眼房内皮, 内皮-前房
Latvian Radzenes endotēlijs, Endotēlijs, radzenes
Polish Śródbłonek rogówki
German Endothel, Kornea-, Endothelium corneae, Korneaendothel, Hornhautendothel
Italian Endotelio della cornea
Dutch Cornea-endotheel, Endotheel, cornea-
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Structure of corneal epithelium (C0459875)

Definition (MSH) Stratified squamous epithelium that covers the outer surface of the CORNEA. It is smooth and contains many free nerve endings.
Definition (CSP) stratified squamous epithelium that covers the outer surface of the cornea; it is smooth and contains many free nerve endings.
Definition (NCI) Stratified squamous epithelium that covers the outer surface of the cornea. (MeSH)
Concepts Tissue (T024)
MSH D019573
SnomedCT 15775008
English Cornea, external epithelium, Anterior Corneal Epithelium, Corneal Epithelium, Corneal Epithelium, Anterior, Epithelium, Anterior Corneal, Epithelium, Corneal, corneal epithelium, Epithelium anterius corneae, Anterior corneal epithelium, Epithelium anterius (Cornea), Epithelium of cornea, cornea epithelium, External epithelium of cornea, Corneal epithelium, Structure of corneal epithelium (body structure), Structure of corneal epithelium
French Épithélium cornéen, Épithélium antérieur de la cornée
Swedish Hornhinneepitel
Czech epitel rohovkový
Portuguese Epitélio Anterior, Epitélio da Córnea, Epitélio Anterior Corneano, Epitélio Anterior da Córnea, Epitélio Corneano
Spanish Epitelio Anterior, Epitelio Anterior de la Córnea, Epitelio Anterior de la Cornea, Epitelio de la Cornea, Epitelio de la Córnea, epitelio externo de la córnea, estructura del epitelio externo de la córnea (estructura corporal), estructura del epitelio externo de la córnea, Epitelio Corneal Anterior, Epitelio Corneal
Finnish Sarveiskalvon epiteeli
Italian Epitelio corneale anteriore, Epitelio corneale
Russian PEREDNEROGOVICHNYI EPITELII, ROGOVITSY EPITELII, ПЕРЕДНЕРОГОВИЧНЫЙ ЭПИТЕЛИЙ, РОГОВИЦЫ ЭПИТЕЛИЙ
Japanese 角膜上皮, 前部角膜上皮, 角膜上皮-前部
Croatian EPITEL ROŽNICE
Latvian Radzenes epitēlijs, Epitēlijs, radzenes, Radzenes epitēlijs, priekšējais, Epitēlijs, priekšējais, radzenes
Polish Nabłonek rogówki
German Epithel, Hornhaut, Epithel, vordere Hornhaut, Hornhautepithel, vorderes, Hornhautepithel, Vorderes Hornhautepithel
Dutch Cornea-epitheel, Cornea-epitheel, anterieur, Epitheel, cornea-
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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