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Riedel's ThyroiditisAka: Fibrous Thyroiditis

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  1. Pathophysiology
    1. Idiopathic fibrosis of Thyroid and adjacent neck
    2. May be associated with mor generalized fibrosis
      1. Idiopathic Multifocal Fibrosclerosis
  2. Epidemiology
    1. Onset age 30 to 60 years
  3. Symptoms
    1. Symptoms related to compression on esophagus, trachea
      1. Stridor or Dyspnea
      2. Dysphagia
  4. Signs
    1. Very firm (rock or wood-like) Thyroid swelling
    2. Hypothyroidism (30%)
  5. Labs
    1. Thyroid Function Tests (T4 Free and TSH)
    2. Antithyroid peroxidase antibodies (>60%)
  6. Imaging
    1. Radioiodine Uptake (Thyroid uptake and scan)
      1. Low uptake (contrast with Grave's Disease)
  7. Diagnosis
    1. Open Thyroid biopsy
  8. Management: Tracheal or esophageal compression
    1. First-line
      1. Surgical decompression
    2. Other agents
      1. Corticosteroids
      2. Methotrexate
      3. Tamoxifen
  9. References
    1. Bindra (2006) Am Fam Physician 73(10):1769

Riedel's thyroiditis (C0154162)

ConceptsDisease or Syndrome (T047)
ICD9245.3
EnglishInvasive fibrous thyroiditis, Invasive thyroiditis, Ligneous thyroiditis, REIDEL STRUMA, Reidel's thyroiditis, RIEDEL STRUMA, Riedel's thyroiditis, Struma fibrosa thyroid, THYROIDITIS CHRONIC <RIEDELS>, THYROIDITIS CHRONIC RIEDELS, Woody thyroiditis
Spanishtiroiditis de Riedel, tiroiditis fibrosa invasiva, tiroiditis lenosa, tiroiditis por estruma fibroso
Parent ConceptsChronic thyroiditis (C0242520), Duplicate concept (C1274013)
SourcesDXP, MTHICD9, QMR, RAM, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)


Fibrous autoimmune thyroiditis (C0271813)

ConceptsPathologic Function (T046)
ICD9245.3
EnglishCHR FIBROUS THYROIDITIS, Chronic fibrous thyroiditis, Fibrous autoimmune thyroiditis, Noninvasive fibrous thyroiditis
Spanishtiroiditis fibrosa autoinmune
Parent ConceptsThyroiditis (C0040147), Chronic thyroiditis (C0242520), Autoimmune thyroiditis (C0920350), Chronic disease of immune function (C1531663)
SourcesDXP, ICD9CM, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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