II. Definitions
- Reactive Infectious Mucocutaneous Eruption (RIME)
- Mucocutaneous eruption after a viral or Bacterial respiratory tract infection
III. Epidemiology
- Most common in children and teens following respiratory tract infection
IV. Causes
- Mycoplasma pneumoniae (original associated, preceding infection)
- Adenovirus
- Chlamydia pneumoniae
- Influenza
V. Signs
- Mucosal lesions (most common)
- Cutaneous lesions (less common)
- Macules and Papules
- Bullous lesions or target lesions suggest alternative diagnosis (e.g. Erythema Multiforme)
VI. Diagnosis
- Two or more mucosal sites demonstrating lesions AND
- Cutaneous sites (if present) affect <10% of skin surface area
VII. Differential Diagnosis
- See Mucositis
- See Oral Ulcer
VIII. Management
- Self-limited and mild manifestations
- Supportive care