II. Definition
- Subcutaneous fat inflammation
III. Causes: Mostly Septal
-
Vasculitis
- Leukocytoclastic Vasculitis (Vasculitis of small veins)
- Superficial Thrombophlebitis (thrombosis of large veins)
- Cutaneous Polyarteritis Nodosa (arteries and arterioles)
- No Vasculitis
- Erythema Nodosum
- Granuloma Annulare
- Necrobiosis Lipoidica
- Necrobiotic xanthogranuloma
- Rheumatoid Nodule
- Scleroderma
IV. Causes: Mostly Lobular
-
Vasculitis
- Nodular Vasculitis
- Associated with Tuberculosis
- Found on lower legs
-
Erythema Induratum (Bazin disease)
- Panniculitis on the back of the calves
- Crohns Disease
- Leprosy
- Lucio's phenomenon
- Rheumatoid Arthritis (Neutrophilic lobular Panniculitis)
- Nodular Vasculitis
- No Vasculitis
- Connective Tissue Disorders
- Crystal deposition in fat
- Gout
- Sclerema neonatorum
- Subcutaneous Fat Necrosis of the newborn
- Post-Corticosteroid Panniculitis
- Tissue Injury
- Cellulitis or other soft tissue infection
- Chemicals (iodides, bromides)
- Cold Panniculitis
- Factitious Panniculitis (injected organic materials such as Saliva, urine beneath skin)
- Lipoatrophy
- Post-radiation Panniculitis
- Traumatic Panniculitis
- Miscellaneous conditions
- Subcutaneous T-Cell Lymphoma
- Sclerosing Panniculitis (Chronic Venous Insufficiency)
- Vascular calcifications (Oxalosis, Calciphylaxis)
V. Signs
- Thick, indurated, red or brown nodular lesions
- Variably tender
- Lipodystrophy (fat atrophy) may follow resolution
VI. References
- Stanway (2015) Panniculitis, DermNet, accessed 12/15/2015
- Requena (2001) J Am Acad Dermatol 45(2):163-83 +PMID:11464178 [PubMed]
- Requena (2001) J Am Acad Dermatol 45(3):325-61 +PMID:11511831 [PubMed]