III. Differential Diagnosis

  1. See Tooth Discoloration
  2. Oral Melanoma
    1. Rare, but devastating outcomes if missed when early, focal

IV. Management

  1. Exclude Melanoma
  2. Eliminate or reduce dosing of causative agents
  3. Consider Tooth Discoloration causes that may be discoloring mucosa as well
  4. Refractory cases
    1. Surgical mucosal stripping of hyperpigmented tissue (e.g. laser, Cryotherapy, scalpel)

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