II. Epidemiology

  1. Rare

III. Pathophysiology

  1. Delayed Nail Growth
  2. Results in nails heaping-up and thickening
  3. May be associated with microvascular permeability
    1. Lymphedema
    2. Pleural Effusion
    3. Hypoalbuminemia

IV. Signs

  1. Convex (heaped-up) nails with loss of lunula
  2. Nail with yellow hue

V. Associated Conditions

  1. Bronchiectasis
  2. Rheumatoid Arthritis
  3. Immunodeficiency (e.g. AIDS)
  4. Chronic Sinusitis
  5. Thiol Medications (e.g. gold Sodium thiomalate)

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